Macfarlane D E, Horner-Bryce J
Acta Paediatr Scand. 1987 May;76(3):474-7. doi: 10.1111/j.1651-2227.1987.tb10502.x.
During a 5-month period, 513 stool samples submitted to the enteric laboratory at the University Hospital of the West Indies were examined for Cryptosporidium. Oocysts were detected in 4.9% of all stools, 7.3% of diarrhoeal stools, 19.5% of stools from malnourished children and 23.7% of stools from malnourished children with diarrhoea. Cryptosporidium was the sole pathogen detected in all 25 positive stools, and was the second most frequent enteric isolate. All cases of cryptosporidiosis occurred in children less than 2.5 years of age. All 15 malnourished children were admitted to hospital where they presented with dehydration (87%), vomiting (93%), fever (100%) and diarrhoea which lasted an average of 15.3 days. Two of these children died. In contrast, dehydration (20%), vomiting (40%) and fever (50%) were less common and diarrhoea less protracted in well-nourished children, four of whom were admitted to hospital. This preliminary report suggests that cryptosporidial gastroenteritis presents with increased frequency and severity in malnourished compared with well-nourished Jamaican children.
在5个月的时间里，对提交至西印度群岛大学医院肠道实验室的513份粪便样本进行了隐孢子虫检测。在所有粪便样本中，4.9%检测出卵囊；腹泻粪便样本中，7.3%检测出卵囊；营养不良儿童的粪便样本中，19.5%检测出卵囊；腹泻的营养不良儿童的粪便样本中，23.7%检测出卵囊。在所有25份阳性粪便样本中，隐孢子虫是唯一检测到的病原体，并且是第二常见的肠道分离病原体。所有隐孢子虫病病例均发生在2.5岁以下儿童中。所有15名营养不良儿童均住院治疗，他们出现脱水（87%）、呕吐（93%）、发热（100%）以及平均持续15.3天的腹泻症状。其中两名儿童死亡。相比之下，营养良好的儿童中脱水（20%）、呕吐（40%）和发热（50%）情况较少见，腹泻持续时间也较短，这些儿童中有4名住院治疗。这份初步报告表明，与营养良好的牙买加儿童相比，营养不良儿童中隐孢子虫性肠胃炎的发病率和严重程度更高。
