Yale Stress Center.
Department of Public Health Sciences.
J Psychopathol Clin Sci. 2022 Oct;131(7):780-792. doi: 10.1037/abn0000771. Epub 2022 Sep 1.
Stress has been linked to increased alcohol use but how stress may increase drinking in social drinkers is not well understood. Negative reinforcement processes may explain this link but the role of specific motivational processes, such as craving, and how these motivational processes are altered by drinking have not been studied. The current study assessed social drinkers ( = 81) for recent quantity and frequency of alcohol intake (quantity and frequency index, QFI) upon study enrollment, who then completed 30 days of electronic daily records of stress, craving, and alcohol intake. Multilevel structural equation models tested if person-averaged (between-person) and daily (within-person) craving mediated the link between stress and later drinking each evening and if recent quantity-frequency of drinking (QFI) moderated these associations. At the between-person level, both greater subjective stress, = .38, 95% confidence interval (CI) [.19, .57], and higher QFI predicted higher levels of craving, = .34, 95% CI [.20, .49]. Higher craving predicted more frequent drinking throughout the study, = .34, 95% CI [.01, .29]. At the within-person level, higher subjective stress predicted higher within-person craving; and the link between craving and later drinking was significant among those who had a higher QFI, = .84, 95% CI [.58, 1.12]. The subjective stress-drinking relationship was mediated by a greater alcohol craving response in social drinkers, and higher the QFI, greater the alcohol craving response. These results indicate that both higher levels of stress and greater recent alcohol intake patterns sensitize the craving response that in turn facilitates later alcohol intake. The findings suggest that higher recent alcohol use predict greater stress-potentiated initiation of drinking via higher craving responses. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
压力与饮酒增加有关,但压力如何增加社交饮酒者的饮酒量尚不清楚。负强化过程可能解释了这种联系,但特定的动机过程(如渴望)的作用,以及这些动机过程如何因饮酒而改变,尚未得到研究。本研究评估了社交饮酒者(n = 81)在研究入组时最近的酒精摄入量和频率(量-频指数,QFI),然后完成了 30 天的电子日常压力、渴望和酒精摄入量记录。多层次结构方程模型测试了个体平均(个体间)和每日(个体内)渴望是否在压力和随后每晚饮酒之间的联系中起中介作用,以及最近的量-频饮酒(QFI)是否调节了这些关联。在个体间水平上,较高的主观压力,β =.38,95%置信区间(CI)[.19,.57],以及较高的 QFI 预测更高水平的渴望,β =.34,95%CI [.20,.49]。较高的渴望预测整个研究期间更频繁的饮酒,β =.34,95%CI [.01,.29]。在个体内水平上,较高的主观压力预测了更高的个体内渴望;在 QFI 较高的个体中,渴望与随后的饮酒之间的联系具有统计学意义,β =.84,95%CI [.58,1.12]。主观压力与饮酒的关系是通过社交饮酒者中更大的酒精渴望反应来介导的,而 QFI 越高,酒精渴望反应越大。这些结果表明,较高的压力水平和更大的近期饮酒模式会使渴望反应更加敏感,从而促进随后的饮酒。研究结果表明,较高的近期饮酒量预示着通过较高的渴望反应,更大的压力会增强饮酒的启动。