Holstad G
Acta Vet Scand. 1986;27(4):584-97. doi: 10.1186/BF03548138.
The precalen-ce of caseous lymphadenitis was surveyed in 36 goat herds in Northern Norway. In each herd, information concerning the occurrence of the disease was obtained from the farmer. Adult animals (1 year of age or older) in 35 herds were examined for superficial swellings, and serum samples were collected from most animals in the herds. The sera were examined for antibodies to Corynebacterium pseudotuber-culosis using the bacterial agglutination test (BAT) and the hemolysis inhibition test (HIT). Gaseous lymphadenitis was diagnosed with certainty in 19 herds. Information from the farmers indicated that the disease indeed oc-curred in these herds, and that the majority had been infected with the disease for many years. The herds had apparently become infected through contact with animals from infected herds. Clinical examina-tions were carried out in 18 of these herds and superficial swellings were found in 26 % of the examined animals. The prevalence of ani-mals with lesions varied from 11 to 40 % among the herds. Of the animals in these herds, 81 % were positive in BAT and 84 % in HIT. The prevalence of positive animals varied from 26 to 99 % in BAT and 28 to 99 % in HIT. The prevalence of seropositive animals was lowest in a herd in which animals were kept separately in stalls. Caseous lymphadenitis could not be diagnosed in 16 herds. In-formation from the farmers indicated that the disease indeed seemed to be absent in 14 of these herds. These 14 herds had no history of contact with animals from herds considered to be infected. However, in the remaining 2 herds, the farmers were somewhat uncertain about the occurrence of the disease. One of these 2 herds had a history of contact with infected herds through participation in a goat “breeding circle”. Only a few of the animals were, however, seropositive and all these had low antibody titres. In 1 newly established herd, a single animal showed a high posi-tive titre in BAT only. All the other animals were negative in both tests. This particular herd consisted of animals obtained both from herds with caseous lymphadenitis and from herds in which the disease was not considered to occur.
对挪威北部36个山羊群中的干酪性淋巴结炎患病率进行了调查。在每个羊群中，从养殖户那里获取有关该疾病发生情况的信息。对35个羊群中的成年动物（1岁及以上）进行了浅表肿胀检查，并从大多数羊群中的动物采集了血清样本。使用细菌凝集试验（BAT）和溶血抑制试验（HIT）检测血清中针对伪结核棒状杆菌的抗体。在19个羊群中确诊有干酪性淋巴结炎。养殖户提供的信息表明，这些羊群确实发生了该疾病，而且大多数羊群已感染该疾病多年。这些羊群显然是通过与感染羊群的动物接触而被感染的。对其中18个羊群进行了临床检查，在26%的受检动物中发现了浅表肿胀。各羊群中出现病变的动物患病率在11%至40%之间。在这些羊群的动物中，81%的动物BAT检测呈阳性，84%的动物HIT检测呈阳性。BAT检测阳性动物的患病率在26%至99%之间，HIT检测阳性动物的患病率在28%至99%之间。在一个将动物单独饲养在畜栏中的羊群中，血清阳性动物的患病率最低。在16个羊群中未诊断出干酪性淋巴结炎。养殖户提供的信息表明，其中14个羊群确实似乎没有该疾病。这14个羊群没有与被认为感染的羊群的动物接触史。然而，在其余2个羊群中，养殖户对该疾病的发生情况有些不确定。这2个羊群中的一个通过参与山羊“育种圈”有与感染羊群接触的历史。然而，只有少数动物血清呈阳性，而且所有这些动物的抗体滴度都很低。在一个新建立的羊群中，只有一只动物仅在BAT检测中显示高阳性滴度。所有其他动物在两项检测中均为阴性。这个特殊的羊群由来自患有干酪性淋巴结炎的羊群和不认为发生该疾病的羊群的动物组成。
