Holstad G
Acta Vet Scand. 1986;27(4):617-22. doi: 10.1186/BF03548141.
In 2 goat herds, one infected with Gorynebacterium pseudo-tuberculosis and one free from the infection,, goats were examined for superficial swellings on the shoulder and chest. All animals in this study had been vaccinated against paratuberculosis before the age of 4 weeks. The vaccine had been applied subcutaneously behind the shoulder. Twenty-two of 40 (55 %) and 31 of 45 (69 %) goats had such lesions in the infected and non-infected herds, respectively. The difference between the herds was not significant, P > 0.05. Swellings found behind the shoulder in 19 goat carcasses derived from 4 herds in which G. pseudotuberculosis infection occurred were examined bacteriologically. No bacteria could be isolated from such lesions in 15 animals, while G. pseudotuberculosis in pure culture was isolated from 3 carcasses, and a mixed bacterial flora from the re-maining carcass. Bacteria could not be isolated from lesions situated behind the shoulder in 7 carcasses from 3 herds free from G. pseudo-tuberculosis infection. It is concluded that most swellings on the shoulder and chest in goats were granulomas resulting from vaccination against paratuber-culosis.
在两个山羊群中，一个感染了伪结核棒状杆菌，另一个未感染，对山羊的肩部和胸部浅表肿胀情况进行了检查。本研究中的所有动物在4周龄前均接种了副结核病疫苗。疫苗是在肩部后方皮下注射的。在感染群和未感染群中，分别有40只山羊中的22只（55%）和45只山羊中的31只（69%）出现了此类病变。两群之间的差异不显著，P>0.05。对来自4个发生伪结核棒状杆菌感染的畜群的19具山羊尸体肩部后方发现的肿胀进行了细菌学检查。15只动物的此类病变中未分离出细菌，3具尸体中分离出了纯培养的伪结核棒状杆菌，其余尸体中分离出了混合菌群。在3个未感染伪结核棒状杆菌的畜群的7具尸体的肩部后方病变中未分离出细菌。得出的结论是，山羊肩部和胸部的大多数肿胀是接种副结核病疫苗引起的肉芽肿。
