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斯里兰卡成年人高血压的患病率及相关因素:采用 JNC7 和 ACC/AHA 2017 指南的 2018-19 年 SLHAS 调查的估计值。

Prevalence and Associations of Hypertension in Sri Lankan Adults: Estimates from the SLHAS 2018-19 Survey Using JNC7 and ACC/AHA 2017 Guidelines.

机构信息

Institute for Health Policy (IHP), LK.

University of Peradeniya, LK.

出版信息

Glob Heart. 2022 Aug 1;17(1):50. doi: 10.5334/gh.1135. eCollection 2022.

Abstract

BACKGROUND

Sri Lanka lacks robust estimates of hypertension (HTN) prevalence owing to few national studies, hindering optimization of control strategies. Evidence on how the revised 2017 American College of Cardiology/American Heart Association (ACC/AHA) HTN definition affects prevalence in low- and middle-income countries (LMICs) is also limited.

OBJECTIVES

To make robust estimates of HTN prevalence in the Sri Lankan adult population, and to assess impact of the ACC/AHA 2017 definitions.

METHODS

Data were sourced from the 2018-2019 first wave of the Sri Lanka Health and Ageing Study (SLHAS), a nationally representative longitudinal study of the noninstitutionalized adult population. After excluding those with missing data and aged <18 years, 6,342 participants (95.1%) were included in the analysis. HTN was defined using either the traditional threshold of systolic BP (SBP) ≥140 mmHg or a diastolic BP (DBP) ≥90 mmHg, or the ACC/AHA 2017 threshold of SBP ≥130 mmHg or DBP ≥80 mmHg, or if taking antihypertensive medication.

RESULTS

Estimated prevalence of HTN in all Sri Lankan adults was 28.2% using the traditional definition, and it doubled to 51.3% when applying the ACC/AHA 2017 definition. Of those classified as hypertensive according to the older and ACC/AHA 2017 definitions, 53.4% and 31.2%, respectively, were previously diagnosed. Of the 23.2% of adults reclassified as hypertensive by the ACC/AHA 2017 definition, 16.6% had a history of CVD or diabetes. Increased prevalence was associated with urban residence, socioeconomic status, obesity, and Muslim ethnicity. Prevalence increased with age, but the increase was steeper in women from their 30s.

CONCLUSIONS

Nearly one in three adult Sri Lankans are hypertensive, requiring antihypertensive treatment. Applying the ACC/AHA 2017 definitions almost doubles numbers, but many of those reclassified would require treatment under recent WHO guidelines. Study findings also suggest that design effects in HTN surveys may be higher than usually assumed.

摘要

背景

由于缺乏全国性研究,斯里兰卡缺乏对高血压(HTN)患病率的准确估计,这阻碍了控制策略的优化。关于修订后的 2017 年美国心脏病学会/美国心脏协会(ACC/AHA)HTN 定义如何影响中低收入国家(LMICs)患病率的证据也很有限。

目的

对斯里兰卡成年人群的 HTN 患病率进行准确估计,并评估 ACC/AHA 2017 定义的影响。

方法

数据来自 2018-2019 年斯里兰卡健康与老龄化研究(SLHAS)的第一波调查,这是一项针对非机构化成年人群的全国代表性纵向研究。在排除了数据缺失和年龄<18 岁的个体后,共有 6342 名参与者(95.1%)纳入分析。HTN 采用以下定义进行诊断:传统阈值为收缩压(SBP)≥140mmHg 或舒张压(DBP)≥90mmHg,或 ACC/AHA 2017 阈值为 SBP≥130mmHg 或 DBP≥80mmHg,或正在服用降压药物。

结果

采用传统定义时,所有斯里兰卡成年人的 HTN 患病率估计为 28.2%,而采用 ACC/AHA 2017 定义时则增加到 51.3%。在根据旧定义和 ACC/AHA 2017 定义被归类为高血压的人群中,分别有 53.4%和 31.2%此前已被诊断为高血压。在被 ACC/AHA 2017 定义重新归类为高血压的 23.2%成年人中,有 16.6%患有心血管疾病或糖尿病。患病率的增加与城市居住、社会经济地位、肥胖和穆斯林种族有关。患病率随年龄增长而增加,但女性从 30 多岁开始增加幅度更大。

结论

近三分之一的成年斯里兰卡人患有高血压,需要进行降压治疗。采用 ACC/AHA 2017 定义几乎将患病人数翻了一番,但根据最近的世界卫生组织指南,许多被重新归类的患者需要治疗。研究结果还表明,HTN 调查中的设计效应可能高于通常假设的值。

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