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胃肠胰神经内分泌肿瘤的影像学进展。

Advances in the imaging of gastroenteropancreatic neuroendocrine neoplasms.

机构信息

Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi 110029, India.

出版信息

World J Gastroenterol. 2022 Jul 14;28(26):3008-3026. doi: 10.3748/wjg.v28.i26.3008.

DOI:10.3748/wjg.v28.i26.3008
PMID:36051339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9331531/
Abstract

Gastroenteropancreatic neuroendocrine neoplasms comprise a heterogeneous group of tumors that differ in their pathogenesis, hormonal syndromes produced, biological behavior and consequently, in their requirement for and/or response to specific chemotherapeutic agents and molecular targeted therapies. Various imaging techniques are available for functional and morphological evaluation of these neoplasms and the selection of investigations performed in each patient should be customized to the clinical question. Also, with the increased availability of cross sectional imaging, these neoplasms are increasingly being detected incidentally in routine radiology practice. This article is a review of the various imaging modalities currently used in the evaluation of neuroendocrine neoplasms, along with a discussion of the role of advanced imaging techniques and a glimpse into the newer imaging horizons, mostly in the research stage.

摘要

胃肠胰神经内分泌肿瘤是一组异质性肿瘤,它们在发病机制、产生的激素综合征、生物学行为等方面存在差异,因此对特定的化疗药物和分子靶向治疗的需求和/或反应也存在差异。各种影像学技术可用于这些肿瘤的功能和形态评估,在每个患者中进行的检查选择应根据临床问题进行定制。此外,随着横断面成像的普及,这些肿瘤在常规放射学实践中越来越多地被偶然发现。本文回顾了目前用于评估神经内分泌肿瘤的各种影像学方法,并讨论了先进影像学技术的作用以及对新的成像领域的展望,这些主要处于研究阶段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/3f8a6352f279/WJG-28-3008-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/ac6c4a77730a/WJG-28-3008-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/065a3c03825f/WJG-28-3008-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/744af7675b21/WJG-28-3008-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/c2b63c52a95d/WJG-28-3008-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/ac7625c7fbfa/WJG-28-3008-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/5bd726bb8cb1/WJG-28-3008-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/b655e185fec6/WJG-28-3008-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/a51c54756c31/WJG-28-3008-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/3f8a6352f279/WJG-28-3008-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/ac6c4a77730a/WJG-28-3008-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/065a3c03825f/WJG-28-3008-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/744af7675b21/WJG-28-3008-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/c2b63c52a95d/WJG-28-3008-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/ac7625c7fbfa/WJG-28-3008-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/5bd726bb8cb1/WJG-28-3008-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/b655e185fec6/WJG-28-3008-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/a51c54756c31/WJG-28-3008-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeeb/9331531/3f8a6352f279/WJG-28-3008-g009.jpg

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Acta Radiol. 2022 Jul;63(7):877-888. doi: 10.1177/02841851211024004. Epub 2021 Jul 5.
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Abdom Radiol (NY). 2021 Oct;46(10):4744-4764. doi: 10.1007/s00261-021-03143-3. Epub 2021 Jun 2.
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Application of low dose pancreas perfusion CT combined with enhancement scanning in diagnosis of pancreatic neuroendocrine tumors.
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Pancreatology. 2021 Jan;21(1):240-245. doi: 10.1016/j.pan.2020.10.046. Epub 2020 Nov 1.
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Radiomics Analysis Based on Diffusion Kurtosis Imaging and T2 Weighted Imaging for Differentiation of Pancreatic Neuroendocrine Tumors From Solid Pseudopapillary Tumors.基于扩散峰度成像和T2加权成像的放射组学分析用于鉴别胰腺神经内分泌肿瘤与实性假乳头状肿瘤
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