肠道炎症与微生物群：超越多样性。
Intestinal inflammation and the microbiota: Beyond diversity.
机构信息
Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.
Departamento Académico de Biología Bioquímica, Facultad de Ciencias de la Salud, Universidad Nacional de Tumbes, Pampa Grande 24000, Tumbes, Peru.
出版信息
World J Gastroenterol. 2022 Jul 14;28(26):3274-3278. doi: 10.3748/wjg.v28.i26.3274.
Abstract
The recent manuscript entitled "Relationship between clinical features and intestinal microbiota in Chinese patients with ulcerative colitis" reported a difference in the intestinal microbiota of patients with ulcerative colitis according to the severity of the colitis. The influence of the intestinal microbiota on the development and progress of gastrointestinal disorders is well established. Besides the diversity in the microbiome, the presence of virulence factors and toxins by commensal bacteria may affect an extensive variety of cellular processes, contributing to the induction of a proinflammatory environment.
摘要
最近的一篇题为“中国溃疡性结肠炎患者的临床特征与肠道微生物群的关系”的手稿报告了根据结肠炎的严重程度，溃疡性结肠炎患者的肠道微生物群存在差异。肠道微生物群对胃肠道疾病的发展和进展的影响已得到充分证实。除了微生物组的多样性外，共生菌的毒力因子和毒素的存在可能会影响广泛的细胞过程，导致促炎环境的诱导。
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