• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肠道炎症与微生物群:超越多样性。

Intestinal inflammation and the microbiota: Beyond diversity.

机构信息

Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.

Departamento Académico de Biología Bioquímica, Facultad de Ciencias de la Salud, Universidad Nacional de Tumbes, Pampa Grande 24000, Tumbes, Peru.

出版信息

World J Gastroenterol. 2022 Jul 14;28(26):3274-3278. doi: 10.3748/wjg.v28.i26.3274.

DOI:10.3748/wjg.v28.i26.3274
PMID:36051343
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9331525/
Abstract

The recent manuscript entitled "Relationship between clinical features and intestinal microbiota in Chinese patients with ulcerative colitis" reported a difference in the intestinal microbiota of patients with ulcerative colitis according to the severity of the colitis. The influence of the intestinal microbiota on the development and progress of gastrointestinal disorders is well established. Besides the diversity in the microbiome, the presence of virulence factors and toxins by commensal bacteria may affect an extensive variety of cellular processes, contributing to the induction of a proinflammatory environment.

摘要

最近的一篇题为“中国溃疡性结肠炎患者的临床特征与肠道微生物群的关系”的手稿报告了根据结肠炎的严重程度,溃疡性结肠炎患者的肠道微生物群存在差异。肠道微生物群对胃肠道疾病的发展和进展的影响已得到充分证实。除了微生物组的多样性外,共生菌的毒力因子和毒素的存在可能会影响广泛的细胞过程,导致促炎环境的诱导。

相似文献

1
Intestinal inflammation and the microbiota: Beyond diversity.肠道炎症与微生物群:超越多样性。
World J Gastroenterol. 2022 Jul 14;28(26):3274-3278. doi: 10.3748/wjg.v28.i26.3274.
2
Gut microbiota in ulcerative colitis: insights on pathogenesis and treatment.溃疡性结肠炎中的肠道微生物群:发病机制和治疗的新见解。
J Dig Dis. 2020 Mar;21(3):147-159. doi: 10.1111/1751-2980.12849.
3
Treatment and mechanism of fecal microbiota transplantation in mice with experimentally induced ulcerative colitis.实验性诱导溃疡性结肠炎小鼠中粪便微生物群移植的治疗和机制。
Exp Biol Med (Maywood). 2021 Jul;246(13):1563-1575. doi: 10.1177/15353702211006044. Epub 2021 Apr 29.
4
Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation.肠道微生物群与溃疡性结肠炎的关系:益生菌和粪便微生物群移植的作用机制及临床应用。
World J Gastroenterol. 2018 Jan 7;24(1):5-14. doi: 10.3748/wjg.v24.i1.5.
5
Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial.多供体强化粪菌移植治疗活动期溃疡性结肠炎:一项随机安慰剂对照试验。
Lancet. 2017 Mar 25;389(10075):1218-1228. doi: 10.1016/S0140-6736(17)30182-4. Epub 2017 Feb 15.
6
The Roles of Inflammation, Nutrient Availability and the Commensal Microbiota in Enteric Pathogen Infection.炎症、营养供应和共生微生物群在肠道病原体感染中的作用。
Microbiol Spectr. 2015 Jun;3(3). doi: 10.1128/microbiolspec.MBP-0008-2014.
7
Evodiamine has therapeutic efficacy in ulcerative colitis by increasing Lactobacillus acidophilus levels and acetate production.吴茱萸碱通过增加嗜酸乳杆菌水平和乙酸产生量对溃疡性结肠炎具有治疗作用。
Pharmacol Res. 2020 Sep;159:104978. doi: 10.1016/j.phrs.2020.104978. Epub 2020 May 30.
8
Fecal microbiota transplantation for ulcerative colitis: a prospective clinical study.粪便微生物群移植治疗溃疡性结肠炎:一项前瞻性临床研究。
BMC Gastroenterol. 2019 Jul 4;19(1):116. doi: 10.1186/s12876-019-1010-4.
9
Beneficial Effects of Fecal Microbiota Transplantation on Ulcerative Colitis in Mice.粪便微生物群移植对小鼠溃疡性结肠炎的有益作用
Dig Dis Sci. 2016 Aug;61(8):2262-2271. doi: 10.1007/s10620-016-4060-2. Epub 2016 Feb 5.
10
Fecal microbiota transplantation for ulcerative colitis.粪便微生物群移植治疗溃疡性结肠炎。
Immunol Med. 2021 Mar;44(1):30-34. doi: 10.1080/25785826.2020.1792040. Epub 2020 Jul 14.

引用本文的文献

1
Maternal high-fat diet increases the susceptibility of offspring to colorectal cancer via the activation of intestinal inflammation.母体高脂饮食通过激活肠道炎症增加后代患结直肠癌的易感性。
Front Nutr. 2023 May 12;10:1191206. doi: 10.3389/fnut.2023.1191206. eCollection 2023.

本文引用的文献

1
Relationship between clinical features and intestinal microbiota in Chinese patients with ulcerative colitis.中国溃疡性结肠炎患者的临床特征与肠道微生物群的关系。
World J Gastroenterol. 2021 Jul 28;27(28):4722-4737. doi: 10.3748/wjg.v27.i28.4722.
2
"Driver-passenger" bacteria and their metabolites in the pathogenesis of colorectal cancer.“驾驶员-乘客”细菌及其代谢产物在结直肠癌发病机制中的作用。
Gut Microbes. 2021 Jan-Dec;13(1):1941710. doi: 10.1080/19490976.2021.1941710.
3
Coronavirus disease-2019 and the intestinal tract: An overview.新型冠状病毒病 2019 与肠道:概述。
World J Gastroenterol. 2021 Apr 7;27(13):1255-1266. doi: 10.3748/wjg.v27.i13.1255.
4
Comparative Transcriptomics of Shiga Toxin-Producing and Commensal and Cytokine Responses in Colonic Epithelial Cell Culture Infections.产志贺毒素大肠杆菌与共生菌的比较转录组学及对结肠上皮细胞培养感染的细胞因子应答。
Front Cell Infect Microbiol. 2020 Oct 26;10:575630. doi: 10.3389/fcimb.2020.575630. eCollection 2020.
5
The Type III Secretion Effector IpaH4.5 Targets NLRP3 to Activate Inflammasome Signaling.III 型分泌效应物 IpaH4.5 靶向 NLRP3 激活炎症小体信号通路。
Front Cell Infect Microbiol. 2020 Sep 30;10:511798. doi: 10.3389/fcimb.2020.511798. eCollection 2020.
6
The gut microbes, Enterococcus and Escherichia-Shigella, affect the responses of heart valve replacement patients to the anticoagulant warfarin.肠道微生物肠球菌和大肠埃希菌-志贺菌属会影响心脏瓣膜置换患者对抗凝剂华法林的反应。
Pharmacol Res. 2020 Sep;159:104979. doi: 10.1016/j.phrs.2020.104979. Epub 2020 Jun 4.
7
Alterations of the Gut Microbiota in Patients With Coronavirus Disease 2019 or H1N1 Influenza.2019 年冠状病毒病或 H1N1 流感患者肠道微生物组的改变。
Clin Infect Dis. 2020 Dec 17;71(10):2669-2678. doi: 10.1093/cid/ciaa709.
8
Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past.新型冠状病毒感染患者的凝血功能障碍:COVID-19、SARS-CoV-1、MERS-CoV 及过去的经验教训。
J Clin Virol. 2020 Jun;127:104362. doi: 10.1016/j.jcv.2020.104362. Epub 2020 Apr 9.
9
The Virulence of O157:H7 Isolates in Mice Depends on Shiga Toxin Type 2a (Stx2a)-Induction and High Levels of Stx2a in Stool.O157:H7菌株在小鼠中的毒力取决于志贺毒素2a(Stx2a)的诱导以及粪便中高水平的Stx2a。
Front Cell Infect Microbiol. 2020 Feb 26;10:62. doi: 10.3389/fcimb.2020.00062. eCollection 2020.
10
Gas gangrene in mammals: a review.哺乳动物气性坏疽综述
J Vet Diagn Invest. 2020 Mar;32(2):175-183. doi: 10.1177/1040638720905830. Epub 2020 Feb 21.