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服用聚乙二醇进行肠道准备后低钠血症诱发全身性癫痫——病例报告及文献简要回顾

Hyponatremia-induced generalized seizure after taking polyethylene glycol for colon preparation-A case report and brief review of the literature.

作者信息

Seyrafian Shiva, Sebghatollahi Vahid, Bastani Bahar

机构信息

Isfahan Kidney Diseases Research Center Isfahan University of Medical Sciences Isfahan Iran.

Isfahan University of Medical Sciences Isfahan Iran.

出版信息

Clin Case Rep. 2022 Aug 26;10(8):e6247. doi: 10.1002/ccr3.6247. eCollection 2022 Aug.

DOI:10.1002/ccr3.6247
PMID:36052026
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9413866/
Abstract

Severe hyponatremia is life-threatening in hospitalized patients. We present an elderly female who developed severe hyponatremia, seizure, and loss of consciousness after taking polyethylene glycol (PEG) solution before colonoscopy. The risk of hyponatremia with PEG for colon preparation in elderly susceptible patients is high. We review the relevant literature.

摘要

严重低钠血症在住院患者中会危及生命。我们报告一位老年女性,她在结肠镜检查前服用聚乙二醇(PEG)溶液后出现严重低钠血症、癫痫发作和意识丧失。对于老年易感患者,使用PEG进行结肠准备时发生低钠血症的风险很高。我们回顾了相关文献。

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Hyponatremia-induced generalized seizure after taking polyethylene glycol for colon preparation-A case report and brief review of the literature.服用聚乙二醇进行肠道准备后低钠血症诱发全身性癫痫——病例报告及文献简要回顾
Clin Case Rep. 2022 Aug 26;10(8):e6247. doi: 10.1002/ccr3.6247. eCollection 2022 Aug.
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引用本文的文献

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Hyponatremic encephalopathy due to polyethylene glycol-based bowel preparation for colonoscopy: A case report.结肠镜检查用聚乙二醇肠道准备导致低钠血症性脑病:一例报告
World J Clin Cases. 2023 Jan 6;11(1):187-192. doi: 10.12998/wjcc.v11.i1.187.

本文引用的文献

1
Serum electrolytes, osmolality, and cleansing quality after bowel prep for colonoscopy with a PEG solution containing ascorbic acid and electrolytes.含抗坏血酸和电解质的 PEG 溶液用于结肠镜检查前肠道准备后的血清电解质、渗透压和清洁质量。
Int J Colorectal Dis. 2022 Feb;37(2):301-307. doi: 10.1007/s00384-021-04058-7. Epub 2021 Oct 31.
2
Iso-osmolar hyponatremia from polyethylene glycol.聚乙二醇引起的等渗性低钠血症
Clin Kidney J. 2020 Jul 13;14(2):715-719. doi: 10.1093/ckj/sfaa087. eCollection 2021 Feb.
3
Hyponatremic Coma after Bowel Preparation.肠道准备后低钠血症昏迷
Eur J Case Rep Intern Med. 2019 Aug 26;6(9):001217. doi: 10.12890/2019_001217. eCollection 2019.
4
Hyponatremic Seizures After Polyethylene Glycol Bowel Preparation: The Elderly at Risk.
Am J Ther. 2018 Nov/Dec;25(6):e779-e780. doi: 10.1097/MJT.0000000000000789.
5
Severe symptomatic hyponatremia associated with the use of polyethylene glycol-based bowel preparation.与使用聚乙二醇肠道准备剂相关的严重症状性低钠血症。
Endocrinol Diabetes Metab Case Rep. 2017 Feb 23;2017. doi: 10.1530/EDM-16-0119. eCollection 2017.
6
Antidepressant-Associated Hyponatremia in the Elderly.老年人中与抗抑郁药相关的低钠血症
J Clin Psychopharmacol. 2016 Dec;36(6):545-549. doi: 10.1097/JCP.0000000000000608.
7
Acute hyponatremia with seizure and mental change after oral sodium picosulfate/magnesium citrate bowel preparation.口服比沙可啶/枸橼酸镁肠道准备后出现伴有癫痫发作和精神改变的急性低钠血症。
Ann Coloproctol. 2014 Dec;30(6):290-3. doi: 10.3393/ac.2014.30.6.290. Epub 2014 Dec 31.
8
Case of inappropriate ADH syndrome: hyponatremia due to polyethylene glycol bowel preparation.抗利尿激素分泌不当综合征病例:聚乙二醇肠道准备导致低钠血症。
World J Gastroenterol. 2014 Sep 14;20(34):12350-4. doi: 10.3748/wjg.v20.i34.12350.
9
Characteristics, prevalence, risk factors, and underlying mechanism of hyponatremia in elderly patients treated with antidepressants: a cross-sectional study.老年抗抑郁药治疗患者低钠血症的特征、患病率、危险因素和潜在机制:一项横断面研究。
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10
Seizures due to hyponatremia following polyethylene glycol preparation; a report of two cases.聚乙二醇制剂后低钠血症所致癫痫发作;两例报告
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