Cho Young Sun, Nam Kyung Min, Park Jang Ho, Byun Sang Hwan, Ryu Jin Suck, Kim Hyun Ju
Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea.
Ann Coloproctol. 2014 Dec;30(6):290-3. doi: 10.3393/ac.2014.30.6.290. Epub 2014 Dec 31.
Sodium picosulfate/magnesium citrate (Picolight Powder), which is used as a bowel preparation for the colon and the rectum, can cause a severe electrolyte imbalance like hyponatremia. When hyponatremia gets severe or occurs rapidly, it can lead to death due to associated complications. We have experienced a case of hyponatremia associated with seizure and loss of consciousness in a 76-year-old woman, who took sodium picosulfate/magnesium citrate as a bowel preparation for colonoscopy. She was taking thiazide and synthroid for the treatment of hypertension and hypothyroidism, respectively, and she had other underlying medical conditions such as a history of seizure and dementia. Following the diagnosis of hyponatremia, we used an intravenous injection of 3% NaCl to normalize the sodium level in her serum, and her associated symptoms soon disappeared.
聚乙二醇电解质散（普乐可复粉）用于结肠和直肠的肠道准备，可导致严重的电解质失衡，如低钠血症。当低钠血症严重或迅速发生时，可能因相关并发症导致死亡。我们遇到过一例76岁女性，她服用聚乙二醇电解质散进行结肠镜检查肠道准备后出现了与癫痫发作和意识丧失相关的低钠血症。她分别服用噻嗪类药物和甲状腺素治疗高血压和甲状腺功能减退，还有癫痫发作史和痴呆等其他基础疾病。诊断为低钠血症后，我们静脉注射3%氯化钠使她血清中的钠水平恢复正常，相关症状很快消失。
