Naspitz C K, Solé D, Wandalsen N
Ann Allergy. 1987 Jul;59(1):21-4.
Two treatment schedules for the initial treatment of acute asthma were evaluated in 150 children. The treatments were randomized so that 75 patients received the beta-2-agonist fenoterol nebulized by facial mask and 75 patients received epinephrine by subcutaneous injection. No significant differences in cardiovascular side effects occurred among the four groups at any time after the initial treatment. We conclude that inhaled fenoterol and subcutaneous epinephrine are equally effective. We recommend the use of inhaled fenoterol for the treatment of acute asthma to avoid the discomfort of injections.
对150名儿童的急性哮喘初始治疗的两种治疗方案进行了评估。治疗是随机分配的，75名患者通过面罩雾化吸入β-2-激动剂非诺特罗，75名患者皮下注射肾上腺素。初始治疗后的任何时间，四组患者在心血管副作用方面均无显著差异。我们得出结论，吸入非诺特罗和皮下注射肾上腺素同样有效。我们建议使用吸入非诺特罗治疗急性哮喘，以避免注射带来的不适。
