多态微生物：癌症的一个新出现的新兴标志。
Polymorphic microbes: a new emerging hallmark of cancer.
机构信息
Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK.
Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, St Mary's Hospital Campus, Imperial College London, London, UK.
出版信息
Trends Microbiol. 2022 Dec;30(12):1131-1134. doi: 10.1016/j.tim.2022.08.004. Epub 2022 Sep 1.
Recognition of the microbiome (and 'polymorphic microbes' within them) as a new emerging hallmark of cancer reflects a wide body of rapidly evolving research. Microbes may be directly carcinogenic, impact host immune responses to promote malignancy, and may be key effectors in determining the efficacy of anticancer therapy. Manipulation of the microbiome is showing promise as an opportunity to influence cancer outcomes.
认识到微生物组（及其内部的“多态微生物”）是癌症的一个新出现的标志，这反映了大量快速发展的研究。微生物可能具有直接致癌性，影响宿主对恶性肿瘤的免疫反应，并且可能是决定抗癌治疗效果的关键因素。对微生物组的操纵显示出作为影响癌症结果的机会的前景。
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