Scientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
Bull Exp Biol Med. 2022 Aug;173(4):459-463. doi: 10.1007/s10517-022-05579-z. Epub 2022 Sep 5.
Parameters of the lipid metabolism and lipid peroxidation-antioxidant defense system in male adolescents with obesity, representatives of European and Mongoloid ethnicity were evaluated. Discriminant analysis revealed the most informative biochemical parameters for obese male adolescents: glutathione-S-transferase, VLDL cholesterol, glutathione peroxidase, reduced glutathione, and SOD activity for obese male Caucasian adolescents and glutathione-S-transferase, VLDL cholesterol, α-tocopherol, and glutathione peroxidase for Mongoloids obese male adolescents. The use of discriminant analysis allows implementing a differentiated ethnicity-oriented approach to prescribing antioxidant drugs in the complex therapy of obesity.
评估了肥胖男性青少年（白人和蒙古人）的脂质代谢和脂质过氧化-抗氧化防御系统参数。判别分析揭示了肥胖男性青少年最具信息量的生化参数：谷胱甘肽 S-转移酶、VLDL 胆固醇、谷胱甘肽过氧化物酶、还原型谷胱甘肽和超氧化物歧化酶活性用于白种人肥胖男性青少年，以及谷胱甘肽 S-转移酶、VLDL 胆固醇、α-生育酚和谷胱甘肽过氧化物酶用于蒙古人肥胖男性青少年。判别分析的使用允许在肥胖症的综合治疗中针对不同种族实施有针对性的抗氧化药物治疗方法。
