Li Ya-Nan, Wang Bin, Huang Ye-Kai, Hu Jin-Song, Sun Jia-Nan
School of Chemical Engineering, Anhui University of Science and Technology, Huainan, China.
School of Biomedical Engineering, Research and Engineering Center of Biomedical Materials, Anhui Medical University, Hefei, China.
Front Chem. 2022 Aug 19;10:967501. doi: 10.3389/fchem.2022.967501. eCollection 2022.
The C-H functionalization of nitrogen-containing heterocycles has emerged as a powerful strategy for the construction of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds. In order to achieve efficient and selective C-H functionalization, electrochemical synthesis has attracted increasing attention. Because electrochemical anodic oxidation is ideal for replacing chemical reagents in C-H functionalization reactions. This mini-review summarizes the current knowledge and recent advances since 2017 in the synthetic utility of electrochemical transformations for the C-H functionalization of nitrogen-containing heterocycles.
含氮杂环的C-H官能化已成为构建碳-碳（C-C）键和碳-杂原子（C-X）键的有力策略。为了实现高效且选择性的C-H官能化，电化学合成已引起越来越多的关注。因为电化学阳极氧化非常适合在C-H官能化反应中替代化学试剂。本综述总结了自2017年以来，关于含氮杂环C-H官能化的电化学转化合成效用的现有知识和最新进展。
