Kapinga Isis K, Kayembe David L, Mwanza Jean-Claude
Department of Ophthalmology, University of Kinshasa, Kinshasa, The Democratic Republic of the Congo.
Department of Ophthalmology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States.
J Curr Glaucoma Pract. 2022 Jan-Apr;16(1):24-30. doi: 10.5005/jp-journals-10078-1360.
To assess the vision-related quality of life (QoL) in Congolese patients with glaucoma and its associated factors.
Ninety-four patients with open-angle glaucoma and 42 age-matched controls were included in the study. QoL was evaluated using the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25). QoL scores were compared between patients and controls. Correlation analysis was run to assess the association of QoL scores with visual function measures. Multivariate linear regression analyses were used to identify demographic and clinical factors that independently predict the overall QoL and its subdomains.
The QoL composite score (QoL-CS) of glaucoma patients (60.2 ± 30.5) was 31.7% lower than that of controls (87.9 ± 9.5), < 0.001. QoL subdomain scores were also significantly lower in glaucoma patients than controls (all < 0.001), with a reduction rate oscillating between 16.5% for color vision and 61.1% for general health. Best-corrected visual acuity (BCVA) of both better seeing eye (BSE) and worst seeing eye (WSE) correlated significantly with QoL-CS (variance: 50.4% and 42.3%, respectively). The correlations of QoL-CS with BSE (variance: 12.9%) and WSE (variance: 16.8%) visual field MD were also significant, but the strengths were weaker than those of BCVA. Every increase of BSE's BCVA by one line improved QoL-CS by 43.4.
Vision-related quality of life in glaucoma patients is significantly impaired in Congolese patients with glaucoma, starting in the early stage of the disease. BCVA of the BSE emerged as an independent significant predictor of overall QoL and most of its components.
Kapinga IK, Kayembe DL, Mwanza JC. Vision-related Quality of Life in Congolese Patients with Glaucoma. J Curr Glaucoma Pract 2022;16(1):24-30.
评估刚果青光眼患者的视力相关生活质量（QoL）及其相关因素。
94例开角型青光眼患者和42例年龄匹配的对照者纳入本研究。使用25项美国国立眼科研究所视觉功能问卷（NEI VFQ - 25）评估生活质量。比较患者和对照者的生活质量得分。进行相关分析以评估生活质量得分与视觉功能指标的相关性。采用多元线性回归分析确定独立预测总体生活质量及其子领域的人口统计学和临床因素。
青光眼患者的生活质量综合评分（QoL - CS）为（60.2±30.5），比对照者（87.9±9.5）低31.7%，P<0.001。青光眼患者的生活质量子领域得分也显著低于对照者（均P<0.001），降低率在色觉的16.5%至总体健康的61.1%之间波动。较好眼（BSE）和较差眼（WSE）的最佳矫正视力（BCVA）均与QoL - CS显著相关（方差分别为50.4%和42.3%）。QoL - CS与BSE（方差：12.9%）和WSE（方差：16.8%）视野平均缺损（MD）也显著相关，但强度弱于BCVA。BSE的BCVA每提高一行，QoL - CS提高43.4。
刚果青光眼患者的视力相关生活质量在疾病早期就受到显著损害。BSE的BCVA是总体生活质量及其大多数组成部分的独立显著预测因素。
卡平加IK，卡扬贝DL，姆万扎JC。刚果青光眼患者的视力相关生活质量。《当代青光眼实践杂志》2022；16(1):24 - 30。
