Sinitsyn M A, Zhukovskaia S A, Popova V B
Antibiot Med Biotekhnol. 1987 May;32(5):341-4.
The process of antibiotic paste washing by repulpation in a solvent, as well as the process of replacing washing of antibiotic filter cakes was studied. This enabled to develop a mathematical model of the process of admixture removing from antibiotic pastes by successive repulpation and replacing washing. The model connects the initial admixture levels in pastes, the filter cake characteristics, the specification requirements to the drug quality and the technological parameters of the process. The results of the studies confirmed the model adequacy.
研究了在溶剂中通过再制浆对抗生素糊剂进行洗涤的过程，以及对抗生素滤饼进行置换洗涤的过程。这使得能够建立一个通过连续再制浆和置换洗涤从抗生素糊剂中去除杂质的过程的数学模型。该模型将糊剂中的初始杂质水平、滤饼特性、对药物质量的规格要求以及该过程的工艺参数联系起来。研究结果证实了该模型的适用性。
