Klimova N E, Grigor'eva V M
Antibiotiki. 1977;22(2):113-7.
During membrane filtration antibiotics belonging to different chemical groups are strictly absorbed on the filters. When the filters are put into liquid thioglycol medium, the residual amounts of the antibiotics on the filters did not prevent the growth of sensitive microflora experimentally added to the drug. When the filter was put onto solid nutrient medium, only resistant forms of the microbes grew as a rule on its surface, the amount of the grown microbes being 26--43 per cent of the added one. The sensitive microbes grew only in the amount of 0.3--1.3 per cent. Subsequently the residues of the antibiotic adsorbed on the filter inhibited the growth of the sensitive and partially resistant microflora.
在膜过滤过程中，属于不同化学组的抗生素会被严格吸附在滤膜上。当将滤膜放入液体硫乙醇酸盐培养基中时，滤膜上抗生素的残留量并未阻止实验添加到培养基中的敏感微生物生长。当将滤膜置于固体营养培养基上时，通常只有微生物的耐药形式在其表面生长，生长的微生物数量为添加量的26% - 43%。敏感微生物的生长量仅为0.3% - 1.3%。随后，吸附在滤膜上的抗生素残留抑制了敏感和部分耐药微生物的生长。
