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一例焊工尘肺患者先接受皮质类固醇治疗,后使用尼达尼布治疗。

A case of welder's pneumoconiosis treated with corticosteroid followed by nintedanib.

作者信息

Kaida Hideyuki, Utsunomiya Takuhide, Koide Yohei, Ueda Yusuke, Wada Kenji, Yoshida Yuji, Kinoshita Yoshiaki, Kushima Hisako, Ishii Hiroshi

机构信息

Department of Respiratory Medicine, Miyakonojo Medical Association Hospital, Miyazaki, Japan.

Department of Respiratory Medicine, Fukuoka University Chikushi Hospital, Fukuoka, Japan.

出版信息

Respir Med Case Rep. 2022 Aug 19;39:101729. doi: 10.1016/j.rmcr.2022.101729. eCollection 2022.

Abstract

A 32-year-old man who had worked as a welder for 13 years was hospitalized for a fever and hemosputum with dyspnea. He was diagnosed with welding fume-associated lung disease with alveolar hemorrhaging and acute respiratory failure. Despite surviving the acute phase with corticosteroid therapy, hypoxemia persisted after a month and a half, requiring home oxygen therapy. As a result of the introduction of nintedanib, his clinical findings gradually improved, and the patient was weaned from oxygen therapy after six months. Inhalation of a large amount of welding fumes in a short period can cause alveolar hemorrhaging and prolonged pulmonary dysfunction.

摘要

一名32岁男性,从事焊工工作13年,因发热、咯血伴呼吸困难入院。他被诊断为与焊接烟尘相关的肺病,伴有肺泡出血和急性呼吸衰竭。尽管通过皮质类固醇治疗度过了急性期,但一个半月后低氧血症仍持续存在,需要家庭氧疗。由于使用了尼达尼布,他的临床症状逐渐改善,6个月后患者停用了氧疗。短期内吸入大量焊接烟尘可导致肺泡出血和长期肺功能障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4ef/9428916/f1722d934822/gr1.jpg

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