Abdi Saeed, Ataei Sara, Abroon Maede, Majma Sanaye Pantea, Abbasinazari Mohammad, Farrokhian Amir
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Clinical Pharmacy, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.
Iran J Pharm Res. 2022 Jun 18;21(1):e127030. doi: 10.5812/ijpr-127030. eCollection 2022 Dec.
Antibiotic-resistant isolates have become a global concern. The standard triple or quadruple therapies have recently become the most effective protocol for eradicating in the gastrointestinal tract. There is evidence regarding the impact of different complementary or dietary supplements on eradication. This review article intended to search electronic bibliographic databases for any clinical studies that evaluated the use of any herbal or dietary supplements to eradicate up to June 2021. A total of 20 human studies met our criteria and were reviewed. Although some herbal medicines have shown their efficacy and safety in eradicating in different clinical trials, more randomized blind, placebo-controlled human trials with a large sample size must be performed to extend our knowledge.
耐抗生素分离株已成为全球关注的问题。标准的三联或四联疗法最近已成为根除胃肠道内（某种病菌）最有效的方案。有证据表明不同的补充剂或膳食补充剂对根除（该病菌）有影响。这篇综述文章旨在检索电子文献数据库，查找截至2021年6月评估使用任何草药或膳食补充剂来根除（该病菌）的临床研究。共有20项人体研究符合我们的标准并进行了综述。尽管一些草药在不同的临床试验中已显示出其在根除（该病菌）方面的有效性和安全性，但仍必须进行更多大样本量的随机双盲、安慰剂对照人体试验，以扩展我们的认知。
