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经颅磁刺激治疗脑卒中后吞咽障碍的研究进展

Research progress on transcranial magnetic stimulation for post-stroke dysphagia.

作者信息

Li Yi, Chen Kerong, Wang Jiapu, Lu Hanmei, Li Xiaoyu, Yang Lei, Zhang Wenlu, Ning Shujuan, Wang Juan, Sun Yi, Song Yu, Zhang Mei, Hou Jianhong, Shi Hongling

机构信息

Department of Rehabilitation Medicine, Third People's Hospital of Yunnan Province, Kunming, China.

Department of Orthopedics, Third People's Hospital of Yunnan Province, Kunming, China.

出版信息

Front Behav Neurosci. 2022 Aug 18;16:995614. doi: 10.3389/fnbeh.2022.995614. eCollection 2022.

Abstract

Dysphagia is one of the most common manifestations of stroke, which can affect as many as 50-81% of acute stroke patients. Despite the development of diverse treatment approaches, the precise mechanisms underlying therapeutic efficacy remain controversial. Earlier studies have revealed that the onset of dysphagia is associated with neurological damage. Neuroplasticity-based transcranial magnetic stimulation (TMS), a recently introduced technique, is widely used in the treatment of post-stroke dysphagia (PSD) by increasing changes in neurological pathways through synaptogenesis, reorganization, network strengthening, and inhibition. The main objective of this review is to discuss the effectiveness, mechanisms, potential limitations, and prospects of TMS for clinical application in PSD rehabilitation, with a view to provide a reference for future research and clinical practice.

摘要

吞咽困难是中风最常见的表现之一,多达50%-81%的急性中风患者会受到影响。尽管有多种治疗方法不断发展,但治疗效果背后的确切机制仍存在争议。早期研究表明,吞咽困难的发病与神经损伤有关。基于神经可塑性的经颅磁刺激(TMS)是一种最近引入的技术,通过促进突触形成、重组、网络强化和抑制来增加神经通路的变化,从而广泛用于治疗中风后吞咽困难(PSD)。本综述的主要目的是讨论TMS在PSD康复临床应用中的有效性、机制、潜在局限性和前景,以期为未来的研究和临床实践提供参考。

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