Nyska M, Porat S, Nyska A, Rousso M, Shoshan S
Arch Orthop Trauma Surg (1978). 1987;106(3):192-4. doi: 10.1007/BF00452209.
In order to improve gliding function of damaged flexor tendons in chickens, we topically applied enriched collagen solution (ECS) to the tendon sheaths of severed tendons. Previous studies using the same experimental model showed improvement of gliding function in the damaged tendons biomechanically and increased collagenolytic activity in the area of the damage after application of ECS. In the present study we evaluated the influence of ECS on peritendinous adhesion formation and on the healing process of the tendons histologically. We found that topically applied ECS reduced adhesion formation, mostly during the first week, without adversely affecting tendon healing or scar maturation.
为了改善鸡受损屈肌腱的滑动功能，我们将富含胶原蛋白溶液（ECS）局部应用于离断肌腱的腱鞘。以往使用相同实验模型的研究表明，应用ECS后，受损肌腱的滑动功能在生物力学上有所改善，损伤区域的胶原酶活性增加。在本研究中，我们从组织学角度评估了ECS对腱周粘连形成和肌腱愈合过程的影响。我们发现，局部应用ECS可减少粘连形成，主要是在第一周，且不会对肌腱愈合或瘢痕成熟产生不利影响。
