Department of Stomatology of Periodontology, Mackay Memorial Hospital, Taipei, Taiwan.
Department of Medicine, Hualien Armed Forces General Hospital, No. 163, Jiali Rd., Xincheng Township, Hualien, 97144, Taiwan.
BMC Oral Health. 2022 Sep 5;22(1):384. doi: 10.1186/s12903-022-02413-w.
Oral health and ocular diseases may be associated with collagen defects and inflammation status. However, the results from prior studies are conflicting. The aim of this study was to explore the association of dental caries and periodontitis with myopia in young adults.
A total of 938 military personnel aged 19-39 years receiving both oral and eye examinations from 2018 through 2020 were included in this study in Taiwan. The severity of myopia was graded as no myopia (diopters > - 0.5, N = 459), low myopia (diopters: - 0.5 to -5.9, N = 225) and high myopia (diopters ≤ - 6.0, N = 254). A multiple logistic regression analysis with adjustments for age, body mass index, systolic blood pressure, smoking, alcohol consumption, missing teeth numbers, blood leucocyte counts, triglycerides, high-density lipoprotein, and uric acid were used to determine the associations of actively dental caries, filled teeth and stage II/III periodontitis with myopia.
The presence of any actively dental caries was significantly associated with a higher risk of any myopia (low or high) (odds ratio [OR] and 95% confidence intervals [95% CI] 1.42 [1.04-1.94]), whereas there was no association for filled teeth. Moreover, the association for stage II/III periodontitis was only observed with high myopia (OR: 1.52 [1.07-2.15]) and was not observed with low myopia.
Our findings suggest that only actively dental caries and a higher severity of periodontitis were associated with myopia among young adults, thus highlighting the dental inflammation status in the oral cavity as a potential link to ocular diseases.
口腔健康和眼部疾病可能与胶原蛋白缺陷和炎症状态有关。然而，先前的研究结果存在矛盾。本研究旨在探讨龋齿和牙周炎与年轻人近视的关系。
本研究共纳入了 2018 年至 2020 年间在台湾接受口腔和眼部检查的 938 名 19-39 岁的军人。近视的严重程度分为无近视（屈光度>-0.5，N=459）、低度近视（屈光度：-0.5 至-5.9，N=225）和高度近视（屈光度≤-6.0，N=254）。采用多因素 logistic 回归分析，调整年龄、体重指数、收缩压、吸烟、饮酒、缺牙数、白细胞计数、甘油三酯、高密度脂蛋白和尿酸等因素，以确定活动性龋齿、补牙和牙周炎 II/III 期与近视的关系。
任何活动性龋齿的存在与任何近视（低度或高度）的风险增加显著相关（比值比[OR]和 95%置信区间[95%CI]为 1.42[1.04-1.94]），而补牙则没有关联。此外，牙周炎 II/III 期仅与高度近视相关（OR：1.52[1.07-2.15]），与低度近视无关。
我们的研究结果表明，只有活动性龋齿和更严重的牙周炎与年轻人近视有关，这突出了口腔内的牙周炎症状态可能是眼部疾病的潜在关联因素。
