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抑郁症与印度尼西亚普通人群中多种疾病风险增加有关。

Depression is Associated with the Increase Risk of Multimorbidity Among the General Population in Indonesia.

作者信息

Sinaga Ivanny O Y, Barliana Melisa I, Pradipta Ivan Surya, Iskandarsyah Aulia, Abdulah Rizky, Alfian Sofa D

机构信息

Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, Indonesia.

Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, Indonesia.

出版信息

J Multidiscip Healthc. 2022 Aug 30;15:1863-1870. doi: 10.2147/JMDH.S372712. eCollection 2022.

Abstract

PURPOSE

Depression is common among patients with chronic disease. However, little is known about the association between depression and the risk of developing multimorbidity. This study aims to identify the association between depression and the incidence of multimorbidity among the general population in Indonesia.

PATIENTS AND METHODS

The national cross-sectional population-based survey used publicly available data from the Indonesian Family Life Survey (IFLS-5) for 2014 among respondents aged ≥15 years. Depression was assessed using the Center for Epidemiologic Studies-Depression (CES-D) scale. The number of chronic diseases and amount of sociodemographic information were obtained from self-reported data. A logistic regression analysis was used to assess the association between depression and multimorbidity, adjusting for confounders. Odds ratios (ORs) with 95% confidence intervals (CIs) were reported.

RESULTS

The study recruited 2222 respondents; the majority of them were male (68.0%) and aged 55-64 years (34.7%). Of the total number of respondents, 69.6% have depression and 36.5% have multimorbidity. The prevalence of depression in respondents increases with age. Depressive symptoms were more likely to report multimorbidity (OR 2.05, 95% CI: 1.66-2.52).

CONCLUSION

Depression is associated with the increased risk of multimorbidity among the general population in Indonesia. Therefore, screening for and treatment of depression for those at risk of developing multimorbidity are urgently needed.

摘要

目的

抑郁症在慢性病患者中很常见。然而,关于抑郁症与发生多种疾病风险之间的关联却知之甚少。本研究旨在确定印度尼西亚普通人群中抑郁症与多种疾病发病率之间的关联。

患者与方法

这项基于全国横断面人群的调查使用了印度尼西亚家庭生活调查(IFLS - 5)2014年公开可得的数据,调查对象为年龄≥15岁的受访者。使用流行病学研究中心抑郁量表(CES - D)评估抑郁症。慢性病数量和社会人口学信息数量来自自我报告数据。采用逻辑回归分析评估抑郁症与多种疾病之间的关联,并对混杂因素进行调整。报告了具有95%置信区间(CIs)的比值比(ORs)。

结果

该研究招募了2222名受访者;其中大多数为男性(68.0%),年龄在55 - 64岁之间(34.7%)。在所有受访者中,69.6%患有抑郁症,36.5%患有多种疾病。受访者中抑郁症的患病率随年龄增长而增加。有抑郁症状的人更有可能报告患有多种疾病(OR 2.05,95% CI:1.66 - 2.52)。

结论

抑郁症与印度尼西亚普通人群中发生多种疾病的风险增加有关。因此,迫切需要对有发生多种疾病风险的人群进行抑郁症筛查和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66a1/9440695/82902b0b95f3/JMDH-15-1863-g0001.jpg

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