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髋部骨折后恢复的轨迹和预后因素:一项纵向队列研究。

Trajectories and prognostic factors for recovery after hip fracture: a longitudinal cohort study.

机构信息

Department Trauma TopCare, ETZ Hospital (Elisabeth-TweeSteden Ziekenhuis), Hilvarenbeekseweg 60, 5022 GC, Tilburg, The Netherlands.

Department of Orthopaedic Surgery, ETZ Hospital (Elisabeth-TweeSteden Ziekenhuis), Hilvarenbeekseweg 60, 5022 GC, Tilburg, The Netherlands.

出版信息

Int Orthop. 2022 Dec;46(12):2913-2926. doi: 10.1007/s00264-022-05561-4. Epub 2022 Sep 6.

Abstract

PURPOSE

The aim of this study was to determine recovery trajectories and prognostic factors for poor recovery in frail and non-frail patients after hip fracture.

METHODS

Patients with a hip fracture aged 65 years and older admitted to a hospital in the Netherlands from August 2015 to November 2016 were asked to complete questionnaires at one week and one, three, six, 12, and 24 months after injury. The questionnaires included the ICEpop CAPability measure for older people, Health Utility Index, and the Hospital Anxiety Depression Scale. Latent class trajectory analysis was used to determine trajectories of recovery. Patient and injury characteristics for favourable and unfavourable outcome were compared with logistic regression.

RESULTS

In total, 696 patients were included of which 367 (53%) patients were frail. Overall, recovery trajectories in frail patients were worse compared to trajectories in non-frail patients. In frail patients, poor recovery was significantly associated with dementia. Lower age was a prognostic factor for good recovery. Immobility, loneliness and weight loss were prognostic for respectively poor capability and symptoms of anxiety and depression. In non-frail patients, recovery after hip fracture was associated with loneliness and the type of hip fracture.

CONCLUSION

Although frailty is associated with poor recovery in older patients with hip fracture, a large proportion of frail patients show good recovery. Loneliness determines poor recovery with anxiety and depressive symptoms.

TRAIL REGISTRATION

ClinicalTrials.gov identifier: NCT02508675 (July 27, 2015).

摘要

目的

本研究旨在确定虚弱和非虚弱的髋部骨折患者的恢复轨迹和预后不良的预测因素。

方法

2015 年 8 月至 2016 年 11 月期间,荷兰一家医院收治的 65 岁及以上髋部骨折患者在受伤后 1 周、1、3、6、12 和 24 个月时被要求完成问卷。问卷包括 ICEpop CAP 老年人能力测量表、健康效用指数和医院焦虑抑郁量表。潜在类别轨迹分析用于确定恢复轨迹。使用逻辑回归比较有利和不利结果的患者和损伤特征。

结果

共纳入 696 例患者,其中 367 例(53%)患者虚弱。总体而言,虚弱患者的恢复轨迹较非虚弱患者差。在虚弱患者中,预后不良与痴呆显著相关。年龄较小是恢复良好的预测因素。不能活动、孤独和体重减轻分别与能力差和焦虑抑郁症状有关。在非虚弱患者中,髋部骨折后的恢复与孤独和髋部骨折类型有关。

结论

尽管虚弱与髋部骨折老年患者的预后不良有关,但相当一部分虚弱患者恢复良好。孤独决定了伴有焦虑和抑郁症状的恢复不良。

注册号

NCT02508675(2015 年 7 月 27 日)。

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