Institute of General Mechanics (IAM), RWTH Aachen University, Eilfschornsteinstr. 18, Aachen, 52062, North Rhine-Westphalia, Germany; Department for Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, Pauwelsstraße 30, Aachen, 52074, North Rhine-Westphalia, Germany; Mechanical and Analysis Design Group (GRANTE), Federal University of Santa Catarina, R. Lauro Linhares, 1850, Florianópolis, 88070-260, Santa Catarina, Brazil.
Institute of General Mechanics (IAM), RWTH Aachen University, Eilfschornsteinstr. 18, Aachen, 52062, North Rhine-Westphalia, Germany.
Med Eng Phys. 2022 Sep;107:103854. doi: 10.1016/j.medengphy.2022.103854. Epub 2022 Jul 19.
We present a systematic and automated stepwise method to calibrate computational models of the spine. For that purpose, a sequential resection study on one lumbar specimen (L2-L5) was performed to obtain the individual contribution of the IVD, the facet joints and the ligaments to the kinematics of the spine. The experimental data was prepared for the calibration procedure in such manner that the FE model could reproduce the average motion of the 10 native spines from former cadaveric studies as well as replicate the proportional change in ROM after removal of a spinal structure obtained in this resection study. A Genetic Algorithm was developed to calibrate the properties of the intervertebral discs and facet joints. The calibration of each ligament was performed by a simple and novel technique that requires only one simulation to obtain its mechanical property. After calibration, the model was capable of reproducing the experimental results in all loading directions and resections.
我们提出了一种系统的、自动化的逐步方法来校准脊柱的计算模型。为此，对一个腰椎标本（L2-L5）进行了顺序切除研究，以获得椎间盘、关节突关节和韧带对脊柱运动学的个体贡献。实验数据经过准备，以便 FE 模型能够再现之前尸体研究中 10 个天然脊柱的平均运动，以及复制在切除研究中切除脊柱结构后 ROM 变化的比例。开发了一种遗传算法来校准椎间盘和关节突关节的特性。通过一种简单而新颖的技术来校准每个韧带的特性，该技术只需要一次模拟即可获得其机械性能。校准后，该模型能够在所有加载方向和切除情况下再现实验结果。
