Department of Rehabilitation Medicine, The Third Affiliated Hospital of Xinxiang Medical University, The East Section of Hualan Avenue, Hongqi District, Xinxiang, 453000, China.
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, 12 Middle Wulumuqi Road, Jing'an District, Shanghai, 200040, China.
Sci Rep. 2022 Sep 6;12(1):15108. doi: 10.1038/s41598-022-17997-0.
The aphasia quotient of Western Aphasia Battery (WAB-AQ) has been used as an inclusion criterion and as an outcome measure in clinical, research, or community settings. The WAB-AQ is also commonly used to measure recovery. This study aimed to quantitatively determine levels of the linguistic deficit by using a cluster analysis of the WAB-AQ in post-stroke aphasia (PSA). 308 patients were extracted from the database. Cutoff scores are defined by mean overlap WAB-AQ scores of clusters by systematic cluster analysis, the method of which is the farthest neighbor element, and the metrics are square Euclidean distance and Pearson correlation, performed on the full sample of WAB-AQ individual subitem scores. A 1-way analysis of variance, with post hoc comparisons conducted, was used to determine whether clusters had significant differences. Three clusters were identified. The scores for severe, moderate, and mild linguistic deficit levels ranged from 0 to 30, 30.1 to 50.3, and 50.4 to 93.7, respectively. For PSA, the cluster analysis of WAB-AQ supports a 3-impairment level classification scheme.
西方失语症成套测验（WAB-AQ）的失语商被用作临床、研究或社区环境中的纳入标准和结果测量指标。WAB-AQ 也常用于衡量康复情况。本研究旨在通过对卒中后失语症（PSA）患者的 WAB-AQ 进行聚类分析，定量确定语言缺陷的程度。从数据库中提取了 308 名患者。通过系统聚类分析，以聚类内平均重叠 WAB-AQ 得分来定义截断分数，最远邻元素是聚类方法，度量是平方欧式距离和 Pearson 相关系数，对 WAB-AQ 个体分项得分的全样本进行分析。采用单因素方差分析，并进行事后比较，以确定聚类是否存在显著差异。共确定了 3 个聚类。严重、中度和轻度语言缺陷水平的得分范围分别为 0 到 30、30.1 到 50.3 和 50.4 到 93.7。对于 PSA，WAB-AQ 的聚类分析支持 3 个损伤水平的分类方案。
