Xu Shuo, Yan Zhijie, Pan Yongquan, Yang Qing, Liu Zhilan, Gao Jiajia, Yang Yanhui, Wu Yufen, Zhang Yanan, Wang Jianhui, Zhuang Ren, Li Chong, Zhang Yongli, Jia Jie
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Xinxiang Medical University, Xinxiang, China.
Behav Neurol. 2021 Nov 9;2021:9417173. doi: 10.1155/2021/9417173. eCollection 2021.
Patients with stroke were compared and correlated from overall and three periods (1-3 months, 4-6 months, and >6 months). Fugl-Meyer assessment for the upper extremity (FMA-UE) and action research and arm test (ARAT) were used to compare the UE motor status between patients with PSA and without PSA through a cross-sectional study among 435 patients. Then, the correlations between the evaluation scale scores of UE motor status and language function of patients with PSA were analyzed in various dimensions, and the language subfunction most closely related to UE motor function was analyzed by multiple linear regression analysis.
We found that the scores of FMA-UE and ARAT in patients with PSA were 14 points ((CI) 10 to 18, < 0.001) and 11 points lower ((CI) 8 to 13, < 0.001), respectively, than those without PSA. Their FMA-UE ( = 0.70, < 0.001) and ARAT ( = 0.62, < 0.001) scores were positively correlated with language function. Regression analysis demonstrated that spontaneous speech ability may account for UE motor function ( = 0.51, < 0.001; = 0.42, < 0.001). Consistent results were also obtained from the analyses within the three time subgroups.
Stroke patients with PSA have worse UE motor performance. UE motor status and language function showed positive correlations, in which spontaneous speech ability significantly accounts for the associations.
对中风患者进行总体及三个时期（1 - 3个月、4 - 6个月和>6个月）的比较与相关性分析。通过对435例患者进行横断面研究，采用上肢Fugl - Meyer评估（FMA - UE）和动作研究臂测试（ARAT）来比较有和没有假性延髓麻痹（PSA）患者的上肢运动状态。然后，从多个维度分析PSA患者上肢运动状态评估量表得分与语言功能之间的相关性，并通过多元线性回归分析确定与上肢运动功能最密切相关的语言子功能。
我们发现，有PSA的患者FMA - UE和ARAT得分分别比没有PSA的患者低14分（(CI) 10至18，<0.001）和11分（(CI) 8至13，<0.001）。他们的FMA - UE（=0.70，<0.001）和ARAT（=0.62，<0.001）得分与语言功能呈正相关。回归分析表明，自发言语能力可能是上肢运动功能的影响因素（=0.51，<0.001；=0.42，<0.001）。在三个时间亚组的分析中也得到了一致的结果。
患有PSA的中风患者上肢运动表现较差。上肢运动状态与语言功能呈正相关，其中自发言语能力是两者关联的重要影响因素。
