• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

牙医接种新冠疫苗的安全性:一项观察性队列研究。

Safety of COVID-19 vaccine delivery by dentists: An observational cohort study.

作者信息

Kagawa Keita, Kuroda Hidetaka, Kaneko Dai, Imura Miki, Imaizumi Uno, Kido Kanta, Tsukimoto Shota, Kurata Shinji, Kishimoto Naotaka, Sanuki Takuro

机构信息

Department of Dental Anesthesiology, Kanagawa Dental University, Yokosuka, Japan.

Department of Anesthesiology, Tokyo University, Tokyo, Japan.

出版信息

J Dent Sci. 2023 Apr;18(2):613-617. doi: 10.1016/j.jds.2022.08.018. Epub 2022 Sep 2.

DOI:10.1016/j.jds.2022.08.018
PMID:36068849
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9437767/
Abstract

BACKGROUND/PURPOSE: Although many coronavirus disease 2019 (COVID-19) vaccine injections have been administered worldwide, the safety of this practice remains unclear. This study aimed to compare the rates of complications associated with COVID-19 vaccines administered by dentists with those of vaccines administered by nurses. This study aimed to evaluate the safety of a vaccination program delivered by dentists.

MATERIALS AND METHODS

This observational cohort study included 537 recipients of the second dose of the Pfizer COVID-19 vaccine, delivered as an intramuscular injection to the upper arm deltoid muscle by dentists or nurses at the study site. Vaccine recipients were divided into two groups according to the vaccination administrator (dentist vs. nurse groups). The rates of complications associated with intramuscular injection technique (numbness in the hand or arm at the time of the injection, vasovagal reflex at the time of the injection, vaccine-related shoulder injury, and prolonged numbness) were examined.

RESULTS

A total of 125 vaccine recipients were included (nurse group, n = 84; dentist group, n = 41). The overall incidence rate of complications was lower in the dentist group (2.4%; 1/41) than in the nurse group (8.3%; 7/84). However, this difference was not statistically significant ( = 0.3).

CONCLUSION

This study suggests that the safety of COVID-19 vaccine administration is comparable between dentists and nurses.

摘要

背景/目的:尽管全球已接种了许多2019冠状病毒病(COVID-19)疫苗,但这种做法的安全性仍不明确。本研究旨在比较牙医接种COVID-19疫苗与护士接种疫苗的并发症发生率。本研究旨在评估牙医实施的疫苗接种计划的安全性。

材料与方法

这项观察性队列研究纳入了537名接受辉瑞COVID-19疫苗第二剂接种的受试者,由研究地点的牙医或护士在上臂三角肌进行肌肉注射。根据疫苗接种管理人员将疫苗接种者分为两组(牙医组与护士组)。检查了与肌肉注射技术相关的并发症发生率(注射时手部或手臂麻木、注射时血管迷走反射、疫苗相关肩部损伤和持续性麻木)。

结果

共纳入125名疫苗接种者(护士组,n = 84;牙医组,n = 41)。牙医组并发症的总体发生率(2.4%;1/41)低于护士组(8.3%;7/84)。然而,这种差异无统计学意义(P = 0.3)。

结论

本研究表明,牙医和护士接种COVID-19疫苗的安全性相当。

相似文献

1
Safety of COVID-19 vaccine delivery by dentists: An observational cohort study.牙医接种新冠疫苗的安全性:一项观察性队列研究。
J Dent Sci. 2023 Apr;18(2):613-617. doi: 10.1016/j.jds.2022.08.018. Epub 2022 Sep 2.
2
A randomized, double-blind, placebo-controlled phase III clinical trial to evaluate the efficacy and safety of SARS-CoV-2 vaccine (inactivated, Vero cell): a structured summary of a study protocol for a randomised controlled trial.一项评估 SARS-CoV-2 疫苗(灭活,Vero 细胞)有效性和安全性的随机、双盲、安慰剂对照 III 期临床试验:一项随机对照试验研究方案的结构化总结。
Trials. 2021 Apr 13;22(1):276. doi: 10.1186/s13063-021-05180-1.
3
Double-Blind, Randomized, Placebo-Controlled Phase III Clinical Trial to Evaluate the Efficacy and Safety of treating Healthcare Professionals with the Adsorbed COVID-19 (Inactivated) Vaccine Manufactured by Sinovac - PROFISCOV: A structured summary of a study protocol for a randomised controlled trial.评价由科兴中维生产的新型冠状病毒(灭活)疫苗对医护人员的有效性和安全性的双盲、随机、安慰剂对照 III 期临床试验 - PROFISCOV:一项随机对照试验的研究方案的结构化总结。
Trials. 2020 Oct 15;21(1):853. doi: 10.1186/s13063-020-04775-4.
4
Safety and tolerability of the novel 2019 coronavirus disease (COVID-19) vaccines among people with epilepsy (PwE): A cross-sectional study.新型 2019 冠状病毒病(COVID-19)疫苗在癫痫患者(PwE)中的安全性和耐受性:一项横断面研究。
Seizure. 2021 Nov;92:2-9. doi: 10.1016/j.seizure.2021.08.001. Epub 2021 Aug 6.
5
Differences in efficiency, satisfaction and adverse events between self-administered intradermal and nurse-administered intramuscular influenza vaccines in hospital workers.医院工作人员自行接种皮内流感疫苗与护士接种肌内流感疫苗在效率、满意度及不良事件方面的差异。
Vaccine. 2015 Nov 27;33(48):6635-40. doi: 10.1016/j.vaccine.2015.10.095. Epub 2015 Oct 31.
6
Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial.抗中东呼吸综合征冠状病毒 DNA 疫苗的安全性和免疫原性:一项 1 期、开放性、单臂、剂量递增试验。
Lancet Infect Dis. 2019 Sep;19(9):1013-1022. doi: 10.1016/S1473-3099(19)30266-X. Epub 2019 Jul 24.
7
Immunogenicity and safety of a novel ten-valent pneumococcal conjugate vaccine in healthy infants in The Gambia: a phase 3, randomised, double-blind, non-inferiority trial.在冈比亚健康婴儿中新型十价肺炎球菌结合疫苗的免疫原性和安全性:一项 3 期、随机、双盲、非劣效性试验。
Lancet Infect Dis. 2021 Jun;21(6):834-846. doi: 10.1016/S1473-3099(20)30735-0. Epub 2021 Jan 28.
8
Side Effects Associated With Homologous and Heterologous COVID-19 Vaccines: A Cross-Sectional Study in Saudi Arabia.与同源和异源新冠疫苗相关的副作用:沙特阿拉伯的一项横断面研究
Cureus. 2023 Jan 21;15(1):e34030. doi: 10.7759/cureus.34030. eCollection 2023 Jan.
9
Final efficacy analysis, interim safety analysis, and immunogenicity of a single dose of recombinant novel coronavirus vaccine (adenovirus type 5 vector) in adults 18 years and older: an international, multicentre, randomised, double-blinded, placebo-controlled phase 3 trial.一项国际、多中心、随机、双盲、安慰剂对照的 III 期临床试验中,重组新型冠状病毒疫苗(腺病毒 5 型载体)在 18 岁及以上成年人中的单次剂量的最终疗效分析、中期安全性分析和免疫原性。
Lancet. 2022 Jan 15;399(10321):237-248. doi: 10.1016/S0140-6736(21)02753-7. Epub 2021 Dec 23.
10
Shoulder Injury Related to Vaccine Administration (SIRVA) in 16 Patients Following COVID-19 Vaccination Who Presented to Chiropractic, Orthopedic, and Physiotherapy Clinics in Hong Kong During 2021.2021 年,在香港的脊医、骨科和物理治疗诊所就诊的 16 名 COVID-19 疫苗接种后出现与疫苗接种相关的肩部损伤(SIRVA)患者。
Med Sci Monit. 2022 Jul 11;28:e937430. doi: 10.12659/MSM.937430.

本文引用的文献

1
Delayed Vasovagal Reaction with Reflex Syncope Following COVID-19 Vaccination.接种 COVID-19 疫苗后出现血管迷走性反应延迟伴反射性晕厥。
Intern Med. 2022 Jul 15;61(14):2167-2170. doi: 10.2169/internalmedicine.9318-21. Epub 2022 May 14.
2
Shoulder Injury Related to COVID-19 Vaccine Administration: A Case Series.与新冠病毒疫苗接种相关的肩部损伤:病例系列
Vaccines (Basel). 2022 Apr 12;10(4):588. doi: 10.3390/vaccines10040588.
3
Empowering dentists to administer COVID-19 vaccines.赋予牙医接种 COVID-19 疫苗的权力。
J Public Health Dent. 2022 Jun;82(3):338-344. doi: 10.1111/jphd.12502. Epub 2022 Jan 19.
4
First Case of 2019 Novel Coronavirus in the United States.美国首例 2019 新型冠状病毒病例。
N Engl J Med. 2020 Mar 5;382(10):929-936. doi: 10.1056/NEJMoa2001191. Epub 2020 Jan 31.
5
Shoulder Injury Related to Vaccine Administration (SIRVA): Petitioner claims to the National Vaccine Injury Compensation Program, 2010-2016.疫苗接种相关肩部损伤(SIRVA):请愿人向 2010-2016 年国家疫苗伤害赔偿计划提出索赔。
Vaccine. 2020 Jan 29;38(5):1076-1083. doi: 10.1016/j.vaccine.2019.11.032. Epub 2019 Nov 23.
6
Best vaccination practice and medically attended injection site events following deltoid intramuscular injection.三角肌肌内注射后的最佳疫苗接种实践及医疗处理的注射部位事件
Hum Vaccin Immunother. 2015;11(5):1184-91. doi: 10.1080/21645515.2015.1017694.
7
A new hypothesis of cause of syncope: trigeminocardiac reflex during extraction of teeth.一个新的晕厥病因假说:拔牙时的三叉心反射。
Med Hypotheses. 2010 Feb;74(2):248-51. doi: 10.1016/j.mehy.2009.09.027. Epub 2009 Oct 7.