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电子晶体学揭示了防腐剂比布可他尔的三螺旋和棒状结构。

Triple helix and rod structures of the antiseptic drug bibrocathol revealed by electron crystallography.

机构信息

Department of Materials and Environmental Chemistry, Stockholm University, SE-106 91, Stockholm, Sweden.

出版信息

Chem Commun (Camb). 2022 Sep 22;58(76):10695-10698. doi: 10.1039/d2cc04209f.

Abstract

Bibrocathol is an active pharmaceutical ingredient that has been used to treat eyelid diseases for over a century, yet its structure has remained unknown. 3D electron diffraction on crystals from a commercial ointment revealed two structures. These results highlight the technique's potential in structure elucidation from microcrystalline mixtures.

摘要

比比考托是一种活性药物成分,一个多世纪以来一直被用于治疗眼睑疾病,但它的结构仍不清楚。对来自商业软膏的晶体进行 3D 电子衍射揭示了两种结构。这些结果突出了该技术从小晶体混合物中进行结构解析的潜力。

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