Wang James C, Fort Callie L, Matl Christina M, Harvey Bailey D, Demke Joshua C, Thomas J Regan, Sidle Douglas M
Department of Otolaryngology - Head and Neck Surgery, Northwestern Medicine, Chicago, Illinois.
Department of Otolaryngology - Head and Neck Surgery, Texas Tech University Health Sciences Center, Lubbock, Texas.
Facial Plast Surg. 2023 Apr;39(2):173-179. doi: 10.1055/a-1938-0343. Epub 2022 Sep 7.
Essential oils (EOs) have been considered as a potential alternative therapy for wound healing and scar reduction. The aim of this article was to provide a comprehensive review examining the effects of EOs on wound healing and scars. PubMed, Cochrane, Ovid, and Embase computerized searches were performed through June 2020. Two independent reviewers conducted data extraction, with search results reviewed by the senior author following the PRISMA protocol. Three manuscripts examining three different EO-containing topical agents were analyzed. Outcomes include healing rate, erythema, pain, pruritus, patient discomfort, physician satisfaction, percent wound reduction, wound/scar surface perimeter area, and qualitative dermatological evaluation. All articles concluded that the EO-containing topical agents resulted in either superior or noninferior outcomes in comparison with controls. - oil obtained lower wound surface perimeter area. Erythema ( = 0.001) was significantly decreased by the peppermint EO-containing topical agent. Physicians also reported greater satisfaction ( < 0.001) in wound appearance with use of the peppermint EO-containing topical agent. A paucity of studies have examined EO use for wound healing and scar reduction. Treatment with EO-containing topical agents resulted in decreased erythema with increased physician satisfaction of wound appearance. Future studies should assess what level of purity is needed for improved results and which EO, or combination of EOs, is most beneficial.
精油（EOs）已被视为伤口愈合和减少疤痕的一种潜在替代疗法。本文的目的是对精油对伤口愈合和疤痕的影响进行全面综述。截至2020年6月，我们在PubMed、Cochrane、Ovid和Embase数据库进行了计算机检索。两名独立评审员进行数据提取，高级作者按照PRISMA协议对检索结果进行审核。分析了三篇研究三种不同含精油局部用药的手稿。结果包括愈合率、红斑、疼痛、瘙痒、患者不适、医生满意度、伤口缩小百分比、伤口/疤痕表面周长面积以及定性皮肤学评估。所有文章均得出结论，与对照组相比，含精油局部用药产生了更好或不逊色的结果。- 油剂使伤口表面周长面积更小。含薄荷精油的局部用药显著降低了红斑（=0.001）。医生们也报告说，使用含薄荷精油的局部用药后，对伤口外观的满意度更高（<0.001）。很少有研究考察精油在伤口愈合和减少疤痕方面的应用。使用含精油局部用药治疗可减少红斑，提高医生对伤口外观的满意度。未来的研究应评估为获得更好效果所需的纯度水平，以及哪种精油或精油组合最为有益。
