Fujikawa Priscilla, Brand Kenneth, Shah Siddharth, Munshi Viraj, Patel Kashyap
Internal Medicine, LewisGale Medical Center, Salem, USA.
Internal Medicine, Edward Via College of Osteopathic Medicine, Blacksburg, USA.
Cureus. 2022 Aug 3;14(8):e27629. doi: 10.7759/cureus.27629. eCollection 2022 Aug.
Multiple myeloma (MM) is a plasma cell dyscrasia in which nearly all cases are diagnosed in patients over 40 years old. This report illustrates a case of a young female who presented with severe generalized weakness, acute kidney injury, hypercalcemia, and anemia. Her symptoms were initially attributed to chronic NSAID and antacid intake, especially given her young age. However, further workup was pursued to rule out other potential diagnoses despite her age. She was ultimately diagnosed with multiple myeloma and started on bortezomib, cyclophosphamide, and dexamethasone. This report emphasizes the importance of maintaining a broad differential diagnosis. Untrained physicians can easily overlook rare cases. Timely diagnosis and treatment are key, and therefore, a high degree of suspicion is crucial for this patient population.
多发性骨髓瘤（MM）是一种浆细胞异常增生性疾病，几乎所有病例均在40岁以上患者中诊断出来。本报告展示了一例年轻女性病例，该患者表现为严重的全身无力、急性肾损伤、高钙血症和贫血。她的症状最初被归因于长期服用非甾体抗炎药和抗酸剂，尤其是考虑到她的年轻。然而，尽管她年轻，但仍进行了进一步检查以排除其他潜在诊断。她最终被诊断为多发性骨髓瘤，并开始使用硼替佐米、环磷酰胺和地塞米松治疗。本报告强调了保持广泛鉴别诊断的重要性。未经培训的医生很容易忽略罕见病例。及时诊断和治疗是关键，因此，对此类患者群体保持高度怀疑至关重要。
