Department of Zoology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab 144411, India.
Department of Chemistry, Salahaddin University-Erbil, Erbil, Iraq; Department of Medical Biochemical Analysis, Cihan University-Erbil, Erbil, Iraq.
Biomed Pharmacother. 2022 Sep;153:113413. doi: 10.1016/j.biopha.2022.113413. Epub 2022 Aug 6.
Phytotherapy, based on medicinal plants, have excellent potential in managing several diseases. A vital part of the healthcare system is herbal medicines, consisting of therapeutic agents with high safety profile and no or least adverse effects. Herbs or medicinal plants show anticancer, antioxidant, and gene-protective activity, which is useful for pharmaceutical industries. In vitro, the extract of antioxidant compounds prevents the growth of colon and liver cancer cells, followed by a dose-dependent method. The screening of extracts is done by using in vitro models. Reactive oxygen species (ROS) and free radicals lead to diseases based on age which promotes oxidative stress. Different types of ROSs available have central roles in the normal physiology and functioning of processes. Herbal or traditional plant medicines have rich antioxidant activity. Despite the limited literature on the health effect of herbal extract or spices. There are many studies examining the encouraging health effects of single phytochemicals instigating from the medicinal plant. This review provides a detailed overview on herbal antioxidants and how application of nanotechnology can improve its biological activity in managing several major diseases, and having no reported side effects.
基于药用植物的植物疗法在治疗多种疾病方面具有巨大潜力。草药是医疗保健系统的重要组成部分，其中包含安全性高、副作用小或几乎没有副作用的治疗剂。草药或药用植物具有抗癌、抗氧化和基因保护作用，这对制药行业很有用。在体外，抗氧化化合物提取物可阻止结肠和肝癌细胞的生长，并呈剂量依赖性。提取物的筛选是通过使用体外模型进行的。活性氧 (ROS) 和自由基会导致基于年龄的疾病，从而促进氧化应激。不同类型的 ROS 在正常生理和过程功能中发挥核心作用。草药或传统植物药具有丰富的抗氧化活性。尽管关于草药提取物或香料健康影响的文献有限，但有许多研究检查了来自药用植物的单一植物化学物质的令人鼓舞的健康影响。本综述详细介绍了草药抗氧化剂，以及纳米技术的应用如何提高其在治疗几种主要疾病中的生物活性，且没有报告副作用。
