School of Biological and Environmental Sciences, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India.
School of Biological and Environmental Sciences, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India.
Biomed Pharmacother. 2022 Sep;153:113400. doi: 10.1016/j.biopha.2022.113400. Epub 2022 Jul 20.
Cordia dichotoma, Indian cherry is one of the traditional medicinal plant well-known for its medicinal properties against variety of diseases primarily hepatocellular disorders. C. dichotoma is moderate size tree that may be found throughout the Himachal Pradesh and commonly called as lashuda. The objective of the present study is to emphasize the phytochemical and pharmacological study with hepatocurative assessment of C. dichotoma to strengthen not only traditional knowledge but also to validate scientific value of its medicinal potential. Furthermore, comprehensive literature information of C. dichotoma has been compiled from the variety of sources, including scientific databases like PubMed and Google Scholar and pertinent publications and books. The information provided in this study covers the years from 1956 to 2021 and KingDraw chemical structure editor software was used to depict the chemical structures of various secondary metabolites such as flavonoids, tannins, alkaloids, proteins carbohydrate and phenolic compounds extracted from the different parts of the C. dichotoma. Although, flavonoids and phenolic compounds are the most prominent phytoconstituents predominantly detected in C. dichotoma, which are known for great antioxidant potential and also they are renowned for their various pharmacological and therapeutic efficiency against various chronic diseases. Overall, the studies included in this review implies that the plant and its extracts have significant therapeutic benefits not only for hepatic but also for a variety of diseases. While further research is required to fully understand the processes underlying C. dichotoma application in various pharmacological activities.
心叶木,印度樱桃,是一种传统的药用植物,因其对多种疾病,尤其是肝细胞紊乱的药用特性而闻名。心叶木是一种中等大小的树,可能在喜马偕尔邦随处可见,通常被称为“lashuda”。本研究的目的是强调心叶木的植物化学和药理学研究及其对肝脏的治疗评估,不仅要加强传统知识,还要验证其药用潜力的科学价值。此外,还从包括 PubMed 和 Google Scholar 等科学数据库以及相关出版物和书籍在内的各种来源编译了关于心叶木的综合文献信息。本研究提供的信息涵盖了 1956 年至 2021 年的年份,使用 KingDraw 化学结构编辑器软件描绘了从心叶木不同部位提取的各种次生代谢物(如类黄酮、单宁、生物碱、蛋白质、碳水化合物和酚类化合物)的化学结构。尽管类黄酮和酚类化合物是在心叶木中检测到的最显著的植物成分,它们以具有强大的抗氧化潜力而闻名,并且以其对各种慢性疾病的各种药理和治疗功效而闻名。总的来说,本综述中包含的研究表明,该植物及其提取物不仅对肝脏,而且对各种疾病都具有重要的治疗益处。虽然需要进一步的研究来充分了解心叶木在各种药理活性中的应用所涉及的过程。