Mertens F, Johansson B, Mandahl N, Heim S, Bennet K, Rydholm A, Willén H, Mitelman F
Cancer Genet Cytogenet. 1987 Sep;28(1):137-44. doi: 10.1016/0165-4608(87)90363-3.
Two liposarcomas were analyzed with chromosome banding technique. The sole chromosomal abnormality in one of the tumors, a mixed type (myxoid and round cell) liposarcoma, was t(12;16)(q13;p11), a rearrangement previously reported to be associated with myxoid liposarcoma. The other tumor, a pleomorphic liposarcoma, displayed massive numerical rearrangements (modal chromosome number 94-112), and numerous, mostly unidentifiable, marker chromosomes. The following clonal structural aberrations were recognized: del(1)(p22), del(1)(q23), t(7;?)(p22;?), i(17q), and t(19;?)(q13;?).
采用染色体显带技术对两例脂肪肉瘤进行了分析。其中一例肿瘤为混合型（黏液样和圆形细胞）脂肪肉瘤，其唯一的染色体异常为t(12;16)(q13;p11)，这是一种先前报道与黏液样脂肪肉瘤相关的重排。另一例肿瘤为多形性脂肪肉瘤，表现出大量的数目重排（众数染色体数为94 - 112）以及众多大多无法识别的标记染色体。识别出以下克隆性结构畸变：del(1)(p22)、del(1)(q23)、t(7;?)(p22;?)、i(17q)和t(19;?)(q13;?)。
