Dermatology Department, Hospital Universitario Virgen del Rocío, Avda. Manuel Siurot s/n, 41013 Sevilla, Spain.
Dermatology Department, Hospital Universitario San Cecilio, Avda. del Conocimiento s/n, 18016 Granda, Spain.
Int J Environ Res Public Health. 2022 Aug 29;19(17):10753. doi: 10.3390/ijerph191710753.
Atopic dermatitis (AD) is a highly frequent chronic inflammatory skin disease. It is important to know how women with AD approach family planning together with their disease. The aim of the present research is to develop and validate a questionnaire for women diagnosed with AD in order to measure their level of desire and gestational information.
A multicenter cross-sectional study was conducted. Women between 18 and 45 years old with mild, moderate, and severe forms of the disease were included and disease-free controls. An exploratory factorial analysis of the primary components and varimax rotation was used to measure the validity of the construct. Cronbach's α was used to measure the reliability of the individual scales and the global questionnaire.
In total, 150 valid questionnaires were included. The final questionnaire consisted of 23 items that converged on six factors. The six scales had adequate reliability: "Pregnancy" (Cronbach's alpha = 0.95), "Conception" (Cronbach's alpha = 0.93), "Concern-information" (Cronbach's alpha = 0.82), "Breastfeeding" (Cronbach's alpha = 0.81), "Sexual life" (Cronbach's alpha = 0.79), and "Family planning" (Cronbach's alpha = 0.67). The total Cronbach's alpha of the questionnaire was 0.94.
This questionnaire is the first specific measurement instrument developed for women with AD of childbearing age that has demonstrated adequate levels of reliability and construct validity. We consider it useful and valuable to study aspects such as family planning in this patient profile, and that can influence their decision to have offspring.
特应性皮炎（AD）是一种高发的慢性炎症性皮肤病。了解 AD 女性如何在疾病的同时规划家庭生育是很重要的。本研究旨在开发和验证用于评估 AD 女性生育愿望和妊娠信息的问卷，并对其进行验证。
本研究为多中心横断面研究，纳入 18-45 岁的轻、中、重度 AD 女性患者和无疾病对照。采用主成分分析和方差极大旋转进行探索性因子分析，以衡量结构的有效性。采用 Cronbach's α 评估个体量表和总体问卷的信度。
共纳入 150 份有效问卷。最终问卷包含 23 个项目，汇聚为 6 个因子。6 个量表具有良好的信度：“妊娠”（Cronbach's α = 0.95）、“受孕”（Cronbach's α = 0.93）、“关注信息”（Cronbach's α = 0.82）、“母乳喂养”（Cronbach's α = 0.81）、“性生活”（Cronbach's α = 0.79）和“生育计划”（Cronbach's α = 0.67）。问卷的总 Cronbach's α 为 0.94。
本问卷是专为育龄期 AD 女性开发的首个特定测量工具，其信度和结构效度均令人满意。我们认为该问卷对于研究此类患者的生育计划等方面是有用且有价值的，这些方面可能会影响其生育决策。
