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用于脉络膜和视网膜疾病的光学相干断层扫描成像技术进展

Advances in Optical Coherence Tomography Imaging Technology and Techniques for Choroidal and Retinal Disorders.

作者信息

Ong Joshua, Zarnegar Arman, Corradetti Giulia, Singh Sumit Randhir, Chhablani Jay

机构信息

Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

Department of Ophthalmology, Doheny Eye Institute, Los Angeles, CA 90095, USA.

出版信息

J Clin Med. 2022 Aug 31;11(17):5139. doi: 10.3390/jcm11175139.

Abstract

Optical coherence tomography (OCT) imaging has played a pivotal role in the field of retina. This light-based, non-invasive imaging modality provides high-quality, cross-sectional analysis of the retina and has revolutionized the diagnosis and management of retinal and choroidal diseases. Since its introduction in the early 1990s, OCT technology has continued to advance to provide quicker acquisition times and higher resolution. In this manuscript, we discuss some of the most recent advances in OCT technology and techniques for choroidal and retinal diseases. The emerging innovations discussed include wide-field OCT, adaptive optics OCT, polarization sensitive OCT, full-field OCT, hand-held OCT, intraoperative OCT, at-home OCT, and more. The applications of these rising OCT systems and techniques will allow for a closer monitoring of chorioretinal diseases and treatment response, more robust analysis in basic science research, and further insights into surgical management. In addition, these innovations to optimize visualization of the choroid and retina offer a promising future for advancing our understanding of the pathophysiology of chorioretinal diseases.

摘要

光学相干断层扫描(OCT)成像在视网膜领域发挥了关键作用。这种基于光的非侵入性成像方式可对视网膜进行高质量的横断面分析,彻底改变了视网膜和脉络膜疾病的诊断与管理。自20世纪90年代初问世以来,OCT技术不断进步,以提供更快的采集时间和更高的分辨率。在本手稿中,我们讨论了OCT技术以及用于脉络膜和视网膜疾病的技术的一些最新进展。所讨论的新兴创新包括广角OCT、自适应光学OCT、偏振敏感OCT、全场OCT、手持式OCT、术中OCT、家用OCT等等。这些新兴的OCT系统和技术的应用将有助于更密切地监测脉络膜视网膜疾病和治疗反应,在基础科学研究中进行更有力的分析,并进一步深入了解手术管理。此外,这些优化脉络膜和视网膜可视化的创新为推进我们对脉络膜视网膜疾病病理生理学的理解提供了一个充满希望的未来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2be4/9457394/d367cea2d29e/jcm-11-05139-g001.jpg

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