Zwanzig-Neun-Fünf Essen GmbH, 45127 Essen, Germany.
Department of Molecular and Cellular SportsMedicine, Institute for Cardiovascular Research and Sports Medicine, German Sports University, 50333 Cologne, Germany.
Nutrients. 2022 Aug 30;14(17):3565. doi: 10.3390/nu14173565.
Chronic obstructive pulmonary disease (COPD) is one of the world's most common diseases and reasons for death. Systemic consequences, especially reduced muscle strength, muscle mass and muscle function, are common and contribute to worsening prognosis and increasing morbidity and mortality. There is strong evidence that physical activity and strength training are effective in prolonging life and lead to better quality of life. Numerous studies have shown that ingestion of protein and carbohydrates after strength training can increase regeneration of strength in young athletes. Recently, we demonstrated that the same effect can be achieved with these macronutrients administered in a meal. Until now, it is not clear if patients with COPD, integrated in regular physical training, respond similarly.
Prescribed strength training, consisting of two sets circular training with machines for big muscle groups was supplemented with a meal rich in protein and carbohydrates. Changes in maximum strength after 24 h were investigated to find out about the impact of this meal on physical capacity. A pilot study was conducted with pragmatic cross-over design.
With nutritive intervention, strength in both knee extensor and chest press were significantly higher than in control training.
The study showed beneficial effects for the intake of protein and carbohydrates in changes in maximum strength. For now, the underlying mechanism remains unclear. Clinical relevance needs further research. The study design and study protocol can be used for further studies with only small adaptions.
慢性阻塞性肺疾病（COPD）是世界上最常见的疾病和死亡原因之一。全身后果，特别是肌肉力量、肌肉质量和肌肉功能下降，很常见，并导致预后恶化，发病率和死亡率增加。有强有力的证据表明，体力活动和力量训练可以延长寿命，并提高生活质量。许多研究表明，力量训练后摄入蛋白质和碳水化合物可以增加年轻运动员的力量恢复。最近，我们证明，这些宏量营养素在一顿饭中摄入也可以达到同样的效果。到目前为止，还不清楚 COPD 患者在接受常规体育锻炼的情况下是否会有类似的反应。
规定的力量训练包括两组用机器进行的大肌肉群循环训练，并辅以富含蛋白质和碳水化合物的膳食。通过调查 24 小时后最大力量的变化，研究这种膳食对身体能力的影响。采用实用交叉设计进行了一项初步研究。
在营养干预下，膝关节伸展和胸部按压的力量明显高于对照组。
该研究显示了蛋白质和碳水化合物摄入对最大力量变化的有益影响。目前，其潜在机制尚不清楚。临床相关性需要进一步研究。研究设计和研究方案可以稍加修改，用于进一步的研究。
