Experimental Center, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Molecules. 2022 Aug 24;27(17):5388. doi: 10.3390/molecules27175388.
Radix Asteris (RA), also known as 'Zi Wan', is the dried root and rhizome of L. f., which has been used to treat cough and asthma in many countries such as China, Japan, Korea and Vietnam. This article summarizes the available information on RA in ancient Chinese medicine books and modern research literature: its botanical properties, traditional uses, chemical composition, pharmacological activity, toxicity and quality control. Studies have shown that RA extracts contain terpenes, triterpenoid saponins, organic acids, peptides and flavonoids, and have various pharmacological activities such as anti-inflammatory, anti-tumor, anti-oxidation, and anti-depression. RA is considered to be a promising medicinal plant based on its traditional use, chemical constituents and pharmacological activities. However, there are few studies on its toxicity and the consistency of its components, which indicates the need for further in-depth studies on the toxicity and quality control of RA and its extracts.
紫菀(RA),又称“紫菀”,是菊科植物的干燥根和根茎,在中国、日本、韩国和越南等国家,被用于治疗咳嗽和哮喘。本文综述了古代中医药书籍和现代研究文献中关于 RA 的现有信息:其植物学特性、传统用途、化学成分、药理活性、毒性和质量控制。研究表明,RA 提取物含有萜类、三萜皂苷、有机酸、肽和类黄酮,具有抗炎、抗肿瘤、抗氧化和抗抑郁等多种药理活性。基于其传统用途、化学成分和药理活性,RA 被认为是一种很有前途的药用植物。然而,关于其毒性及其成分的一致性的研究较少,这表明需要进一步深入研究 RA 及其提取物的毒性和质量控制。