Fox P C, Sarras A K, Bowers M R, Drosos A A, Moutsopoulos H M
Clin Exp Rheumatol. 1987 Apr-Jun;5(2):123-6.
Forty-two patients with autoimmune rheumatic diseases were evaluated for oral-dental findings and a biopsy of labial minor salivary glands was obtained. Stimulated parotid salivary gland function was assessed and levels of total protein, chloride and albumin in these secretions measured. The patients were stratified into three groups according to the severity of labial gland histopathology (normal histology, 1+ and 2+). Individuals with chronic inflammatory disease of the minor salivary glands had no decrease in stimulated parotid salivary flow but were found to have a greater incidence of oral soft tissue changes commonly associated with salivary dysfunction. However, there were no statistically significant differences in total protein or chloride levels between the groups and no albumin was detected in any samples. These data suggest that stimulated parotid function may be a poor indicator of the extent of salivary involvement in individuals with autoimmune-mediated salivary gland disease.
对42例自身免疫性风湿疾病患者进行了口腔牙齿检查，并获取了唇小唾液腺活检样本。评估了刺激后的腮腺唾液腺功能，并测量了这些分泌物中总蛋白、氯化物和白蛋白的水平。根据唇腺组织病理学严重程度（正常组织学、1+和2+）将患者分为三组。患有小唾液腺慢性炎症疾病的个体，其刺激后的腮腺唾液流量没有减少，但发现与唾液功能障碍相关的口腔软组织变化发生率更高。然而，各组之间总蛋白或氯化物水平没有统计学上的显著差异，且所有样本中均未检测到白蛋白。这些数据表明，对于自身免疫介导的唾液腺疾病患者，刺激后的腮腺功能可能不是唾液受累程度的良好指标。
