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有和无干燥综合征组织学表现的自身免疫性风湿病患者的唾液化学

Sialochemistry of patients with autoimmune rheumatic disease with and without histological manifestations of Sjögren's syndrome.

作者信息

Tsianos E B, Tzioufas A G, Mavridis A K, Sarras A K, Papadimitriou C S, Tsolas O, Moutsopoulos H M

出版信息

Ann Rheum Dis. 1985 Jun;44(6):412-4. doi: 10.1136/ard.44.6.412.

DOI:10.1136/ard.44.6.412
PMID:3874609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1001662/
Abstract

Fifty-one patients with autoimmune rheumatic diseases underwent biopsy of the labial minor salivary glands. These patients were divided according to histopathology of lip biopsies into three groups (negative lip biopsy, 1+ and 2+). From all the patients stimulated parotid salivary flow was measured. In the saliva sodium, potassium, magnesium, alpha-amylase, and immunoglobulin levels (IgA, IgG, IgM) were measured. It is shown that patients with advanced chronic inflammatory disease of the minor salivary glands have decreased stimulated salivary flow. However, no statistically significant differences were observed in the biochemical markers tested between the histopathological groups examined.

摘要

51例自身免疫性风湿性疾病患者接受了唇小唾液腺活检。这些患者根据唇部活检的组织病理学分为三组（唇部活检阴性、1+和2+）。测量了所有患者腮腺刺激唾液流量。检测了唾液中的钠、钾、镁、α淀粉酶和免疫球蛋白水平（IgA、IgG、IgM）。结果显示，小唾液腺晚期慢性炎症患者的刺激唾液流量降低。然而，在所检查的组织病理学组之间，所检测的生化标志物未观察到统计学上的显著差异。

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引用本文的文献

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The diagnosis value of beta 2-microglobulin and immunoglobulins in primary Sjögren's syndrome.β2-微球蛋白和免疫球蛋白在原发性干燥综合征中的诊断价值。
Clin Rheumatol. 1995 Mar;14(2):151-6. doi: 10.1007/BF02214934.

本文引用的文献

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1958 Revision of diagnostic criteria for rheumatoid arthritis.1958年类风湿关节炎诊断标准修订版。
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