Arai Shinji, Suzuki Hiroko, Hayashi Shion, Inagaki Risako, Haseoka Takashi, Hikoya Akiko, Komori Miwa, Shimizu Tamami, Muhammad Nazmul Haque, Hotta Yoshihiro, Sato Miho
Department of Ophthalmology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, 431-3125, Hamamatsu City, Shizuoka, Japan.
Department of Ophthalmology, Yamagata University Faculty of Medicine, 2-2-2 Iidanishi, 990-9585, Yamagata City, Yamagata, Japan.
Jpn J Ophthalmol. 2022 Nov;66(6):572-578. doi: 10.1007/s10384-022-00939-8. Epub 2022 Sep 9.
To evaluate intraocular pressure (IOP) at different gaze positions in patients with highly myopic strabismus (HMS).
Nonrandomized, prospective, observational study.
This study included 18 eyes of 14 patients with HMS and 51 eyes of 51 age-matched controls without strabismus; these were further divided into two groups based on refractive errors: > -6.00 diopter (D) (n = 22 eyes) and ≤ -6.00 D (n = 29 eyes). IOP was measured in primary and side gazes and compared within and among groups. The relationships between IOPs and axial length, angle of globe dislocation measured on magnetic resonance imaging, strabismus angle, and degree of abduction deficit were studied.
The HMS group showed higher IOP in abduction (19.3 ± 4.9 mmHg) than in the primary (12.5 ± 4.3 mmHg) and adducting positions (13.0 ± 3.3 mmHg), (p < 0.001). The IOP in the adducting position in the HMS group (13.0 ± 3.3 mmHg) was lower than in the control groups both with (17.6 ± 3.5 mmHg) and without (16.9 ± 4.1 mmHg) high myopia, ; (p < 0.001 and = 0.003). The difference in IOP between abduction and adduction was significantly larger in the HMS group (6.4 ± 4.6 mmHg) compared to others (p < 0.001) and positively correlated with the strabismus angle and the angle of globe dislocation and negatively with abduction deficit.
The IOP of patients with HMS changes dramatically on side gazes, therefore, care should be taken while measuring IOP.
评估高度近视性斜视（HMS）患者在不同注视位置时的眼压（IOP）。
非随机、前瞻性观察性研究。
本研究纳入了14例HMS患者的18只眼以及51例年龄匹配的无斜视对照者的51只眼；根据屈光不正情况将其进一步分为两组：>-6.00屈光度（D）（n = 22只眼）和≤-6.00 D（n = 29只眼）。在第一眼位和旁注视位测量眼压，并在组内和组间进行比较。研究眼压与眼轴长度、磁共振成像测量的眼球移位角度、斜视角度以及外展不足程度之间的关系。
HMS组在外展位的眼压（19.3±4.9 mmHg）高于第一眼位（12.5±4.3 mmHg）和内收位（13.0±3.3 mmHg），（p<0.001）。HMS组内收位的眼压（13.0±3.3 mmHg）低于有高度近视（17.6±3.5 mmHg）和无高度近视（16.9±4.1 mmHg）的对照组，（p<0.001和=0.003）。与其他组相比，HMS组外展和内收时的眼压差异显著更大（6.4±4.6 mmHg）（p<0.001），且与斜视角度和眼球移位角度呈正相关，与外展不足呈负相关。
HMS患者的眼压在旁注视时变化显著，因此，测量眼压时应谨慎。
