Strange C, Heffner J E, Collins B S, Brown F M, Sahn S A
Chest. 1987 Aug;92(2):367-9. doi: 10.1378/chest.92.2.367.
We describe a fatal complication of transbronchial biopsy in a patient with pulmonary parenchymal amyloidosis. Hemorrhage after biopsy required intubation and positive-pressure ventilation that resulted in massive arterial air embolism. Postmortem findings suggested that the bleeding and air embolism were related to persistent patency of biopsied blood vessels infiltrated with amyloid. Patients with pulmonary amyloidosis may be at increased risk of major complications after transbronchial biopsy.
我们描述了一名肺实质淀粉样变性患者经支气管活检的致命并发症。活检后出血需要插管和正压通气，这导致了大量动脉空气栓塞。尸检结果表明，出血和空气栓塞与被淀粉样物质浸润的活检血管持续通畅有关。肺淀粉样变性患者经支气管活检后发生主要并发症的风险可能会增加。
