Institute for History of Medicine and Science Studies, University of Lübeck.
Ber Wiss. 2022 Sep;45(3):415-427. doi: 10.1002/bewi.202200032.
Hans-Jörg Rheinberger constructed his historical epistemology of epistemic things by analyzing experimental practices in molecular biology during the 1970s and 80s. With genetic sequencing and multi-omics approaches, data has become a new resource in the life sciences, questioning the applicability of his concept of experimental system. By historicizing Rheinberger's epistemology, the paper focuses on its relatedness to Ludwik Fleck's notion of an aviso of resistance and points to a gradual shift in Rheinberger's emphasis, moving from an initial focus on writing and its differentiality to work on materials, preparations, and representations. By anchoring visualization in these material practices, Rheinberger also sheds new light on the changing conditions of experimentation in the life sciences due to big data, where visualization emphasizes patterns and correlations rather than substrates.
汉斯-约尔格·莱茵贝格通过分析 20 世纪 70 年代和 80 年代分子生物学中的实验实践,构建了他的知识事物的历史认识论。随着基因测序和多组学方法的出现,数据已成为生命科学中的一种新资源,这对他的实验系统概念的适用性提出了质疑。本文通过将莱茵贝格的认识论历史化,重点关注它与路德维希·弗莱克的抵抗警告概念的相关性,并指出莱茵贝格的重点逐渐发生转变,从最初对写作及其差异性的关注转向对材料、准备和表示的关注。通过将可视化固定在这些物质实践中,莱茵贝格也为生命科学中由于大数据而导致的实验条件的变化提供了新的视角,在大数据中,可视化强调模式和相关性,而不是基质。