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急性A型主动脉夹层全弓置换术与近端主动脉置换术:积极治疗与保守治疗对比

Total arch replacement versus proximal aortic replacement in acute type A aortic dissection: Aggressive versus conservative.

作者信息

Jubouri Matti, Ansari Daniyal Matin, Zaqout Feras, Bashir Mohamad, Idhrees Mohammed

机构信息

Hull York Medical School, University of York, York, UK.

St. George's Hospital Medical School, London, UK.

出版信息

J Card Surg. 2022 Dec;37(12):4267-4268. doi: 10.1111/jocs.16916. Epub 2022 Sep 10.

Abstract

BACKGROUND

Acute type A aortic dissection (ATAAD) is a life-threatening medical condition requiring urgent surgical attention. It is estimated that 50% of ATAAD die within 24 h of onset, with the mortality rate is increasing by 1%-2% every additional hour without prompt intervention. A variety of ATAAD surgical repair techniques exist which has sparked controversy within the literature, with the main two strategies being proximal aortic replacement (PAR) and total arch replacement (TAR). Nevertheless, the question of which of these two strategies if the more optimal is still debatable.

AIMS

This commentary aims to discuss the recent study by Sa and colleagues which presents a pooled analysis of Kaplan-Meier-derived individual patient data from studies with follow-up comparing aggressive (TAR) and conservative (PAR) approaches to manage ATAAD patients.

METHODS

A comprehensive literature search was performed using multiple electronic databases including PubMed, Ovid, Google Scholar, EMBASE, and Scopus to collate the relevant research evidence.

RESULTS

The more aggressive TAR approach for treating ATAAD seems to yield more favorable results including more optimal long-term survival as well as a lower need for reoperation. The frozen elephant trunk (FET) technique can be considered the mainstay TAR technique.

CONCLUSION

It is valid to conclude that TAR with FET is the superior strategy for managing ATAAD patients.

摘要

背景

急性A型主动脉夹层(ATAAD)是一种危及生命的疾病,需要紧急手术治疗。据估计,50%的ATAAD患者在发病后24小时内死亡,若不及时干预,死亡率每增加一小时就上升1%-2%。存在多种ATAAD手术修复技术,这在文献中引发了争议,主要的两种策略是近端主动脉置换(PAR)和全弓置换(TAR)。然而,这两种策略中哪种更优仍存在争议。

目的

本评论旨在讨论萨及其同事最近的研究,该研究对来自比较积极(TAR)和保守(PAR)方法治疗ATAAD患者的随访研究中Kaplan-Meier推导的个体患者数据进行了汇总分析。

方法

使用包括PubMed、Ovid、谷歌学术、EMBASE和Scopus在内的多个电子数据库进行全面的文献检索,以整理相关研究证据。

结果

更积极的TAR方法治疗ATAAD似乎能产生更有利的结果,包括更优的长期生存率以及更低的再次手术需求。冷冻象鼻(FET)技术可被视为主要的TAR技术。

结论

得出FET的TAR是治疗ATAAD患者的更优策略这一结论是合理的。

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