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过去15年中翻修膝关节置换手术无指数级增长:来自国家关节注册中心的分析

No exponential rise in revision knee replacement surgery over the past 15 years: an analysis from the National Joint Registry.

作者信息

Sabah S A, Knight R, Alvand A, Murray D W, Petrou S, Beard D J, Price A J

机构信息

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK; Nuffield Orthopaedic Centre, Oxford, UK.

Oxford Clinical Trials Research Unit, Centre for Statistics in Medicine, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, UK.

出版信息

Osteoarthritis Cartilage. 2022 Dec;30(12):1670-1679. doi: 10.1016/j.joca.2022.08.016. Epub 2022 Sep 7.

Abstract

OBJECTIVE

To investigate trends in the incidence rate and the main indication for revision knee replacement (rKR) over the past 15 years in the UK.

METHOD

Repeated national cross-sectional study from 2006 to 2020 using data from the National Joint Registry (NJR). Crude incidence rates were calculated using population statistics from the Office for National Statistics.

RESULTS

Annual total counts of rKR increased from 2,743 procedures in 2006 to 6,819 procedures in 2019 (149% increase). The incidence rate of rKR increased from 6.3 per 100,000 adults in 2006 (95% CI 6.1 to 6.5) to 14 per 100,000 adults in 2019 (95% CI 14 to 14) (122% increase). Annual increases in the incidence rate of rKR became smaller over the study period. There was a 43.6% reduction in total rKR procedures in 2020 (during the Covid-19 pandemic) compared to 2019. Aseptic loosening was the most frequent indication for rKR overall (20.7% procedures). rKR for aseptic loosening peaked in 2012 and subsequently decreased. rKR for infection increased incrementally over the study period to become the most frequent indication in 2019 (2.7 per 100,000 adults [95% CI 2.6 to 2.9]). Infection accounted for 17.1% first linked rKR, 36.5% second linked rKR and 49.4% third or more linked rKR from 2014 to 2019.

CONCLUSIONS

Recent trends suggest slowing of the rate of increase in the incidence of rKR. Infection is now the most common indication for rKR, following recent decreases in rKR for aseptic loosening. Infection was prevalent in re-revision KR procedures.

摘要

目的

调查过去15年英国翻修膝关节置换术(rKR)的发病率趋势及主要指征。

方法

利用国家关节注册处(NJR)的数据,于2006年至2020年开展重复的全国横断面研究。采用国家统计局的人口统计数据计算粗发病率。

结果

rKR的年度总数从2006年的2743例增加到2019年的6819例(增长149%)。rKR的发病率从2006年每10万成年人中的6.3例(95%置信区间6.1至6.5)增加到2019年每10万成年人中的14例(95%置信区间14至14)(增长122%)。在研究期间,rKR发病率的年度增长幅度变小。与2019年相比,2020年(新冠疫情期间)rKR的总数减少了43.6%。无菌性松动是rKR总体上最常见的指征(占手术的20.7%)。无菌性松动的rKR在2012年达到峰值,随后下降。在研究期间,感染相关的rKR逐渐增加,在2019年成为最常见的指征(每10万成年人中有2.7例[95%置信区间2.6至2.9])。2014年至2019年,感染占首次翻修rKR的17.1%、第二次翻修rKR的36.5%以及第三次或更多次翻修rKR的49.4%。

结论

近期趋势表明rKR发病率的增长速度放缓。随着近期无菌性松动相关rKR的减少,感染现已成为rKR最常见的指征。感染在再次翻修膝关节置换手术中很普遍。

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