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母亲贫血对埃塞俄比亚西北部新生儿低出生体重的影响。

The effect of maternal anaemia on low birth weight among newborns in Northwest Ethiopia.

机构信息

Department of Public Health, College of Health Sciences, Debre Tabor University, P.o.Box: 031, Debre Tabor, Ethiopia.

Department of Medical Laboratory Sciences, College of Health Sciences, Debre Tabor University, P.o.Box: 272, Debre Tabor, Ethiopia.

出版信息

Sci Rep. 2022 Sep 10;12(1):15280. doi: 10.1038/s41598-022-19726-z.

Abstract

Low birth weight is an indicator of maternal-related multifactorial problems such as malnutrition, illness, and work overload. As a result, low birth weight is associated with maternal anaemia, and both of them were significant public health issues in developing nations. Low birth weight and anaemia are caused by insufficient nutrient intake, which is especially severe during pregnancy. So, this study aimed to assess the effect of maternal anaemia during the late trimester on low birth weight among newborns in Northwest Ethiopia. A systematic random sampling technique was used to select 211 participants for the primary data collection. Face-to-face interviews were used to collect data, while blood samples were collected using standard operating procedures. For further analysis, the data file was imported into Stata version 16 (MP) software. The binary logistic regression model was used to investigate significant factors related to low birth weight. Finally, the statistical significance of the variables was determined using a p value of ≤ 0.05. The prevalence of anaemia among pregnant women in the late trimester and newborns was 34 (16.11%, 95% CI: 11.42, 21.78) and 64 (30.33%, 95% CI: 24.20, 37.01), respectively. The mean ± standard deviation of the newborn babies' weight was 3.19 ± 0.49 kg. The proportion of low birth weight among newborns was 26 (12.32%, 95% CI: 8.20, 17.53%). The independent effect of anaemia on low birth weight was 4.19 times while all other factors were constant (COR = 4.19, 95% CI: 1.70, 10.30). Maternal educational status [unable to read and write (AOR = 10.94, 95% CI: 1.74, 68.58) and attained secondary education (AOR = 8.06, 95% CI: 1.53, 42.36)], and maternal anaemia (AOR = 3.51, 95% CI: 1.29, 9.55) were associated with low birth weight after adjusting with all other variables. In this study, the proportion of low birth weight was high. Here, maternal anaemia alone had a significant independent role in the development of low birth weight. Maternal education status and anaemic conditions were associated with low birth weight among newborns. Early detection and treatment of maternal anaemia during pregnancy is crucial with the usual nutritional-related care.

摘要

低出生体重是与母亲相关的多种因素问题的指标,如营养不良、疾病和工作负荷过重。因此,低出生体重与母亲贫血有关,两者都是发展中国家的重大公共卫生问题。低出生体重和贫血是由于营养摄入不足引起的,尤其是在怀孕期间更为严重。因此,本研究旨在评估埃塞俄比亚西北部孕妇晚期贫血对新生儿低出生体重的影响。采用系统随机抽样技术选择 211 名参与者进行主要数据收集。采用面对面访谈收集数据,同时采用标准操作规程采集血样。为了进一步分析,将数据文件导入 Stata 版本 16(MP)软件。采用二项逻辑回归模型调查与低出生体重相关的显著因素。最后,使用 p 值≤0.05 确定变量的统计学意义。孕妇晚期贫血和新生儿贫血的患病率分别为 34(16.11%,95%CI:11.42%,21.78%)和 64(30.33%,95%CI:24.20%,37.01%)。新生儿体重的平均值±标准差为 3.19±0.49kg。新生儿低出生体重的比例为 26(12.32%,95%CI:8.20%,17.53%)。贫血对低出生体重的独立影响是其他所有因素不变时的 4.19 倍(COR=4.19,95%CI:1.70%,10.30%)。在调整所有其他变量后,母亲的教育程度[无法读写(AOR=10.94,95%CI:1.74%,68.58%)和完成中学教育(AOR=8.06,95%CI:1.53%,42.36%)]和母亲贫血(AOR=3.51,95%CI:1.29%,9.55%)与低出生体重有关。在这项研究中,低出生体重的比例很高。在这里,贫血本身在低出生体重的发展中具有显著的独立作用。母亲的教育程度和贫血状况与新生儿的低出生体重有关。在怀孕期间早期发现和治疗母亲贫血,并进行常规营养相关护理至关重要。

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