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树脂基材料控制体外侵蚀条件下人牙本质渗透性:液压传导率、共聚焦显微镜和 FTIR 研究。

Resin-based materials to control human dentin permeability under erosive conditions in vitro: A hydraulic conductance, confocal microscopy and FTIR study.

机构信息

Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.

Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.

出版信息

Dent Mater. 2022 Oct;38(10):1669-1678. doi: 10.1016/j.dental.2022.08.012. Epub 2022 Sep 8.

DOI:10.1016/j.dental.2022.08.012
PMID:36089408
Abstract

OBJECTIVES

To characterize the behavior of three different polymeric agents before and after an erosive challenge on dentin permeability, to analyze their degradation in both conditions, and to analyze their degree of conversion (DC).

METHODS

The permeability of human dentin disks (1.0 ± 0.2 mm) was measured with smear layer, after its removal, after treatment (LpTreat) with Gluma Desensitizer, PRG Barrier Coat (PBC) or Icon infiltrant (n = 11/group) and after exposure to citric acid (LpEro) (6%, pH 2.1, 1 min). The specimens were analyzed under a Laser Scanning Confocal Microscope (n = 2/group) and the products' DC were calculated. Data were subjected to 2-way repeated measures ANOVA and post-hoc Bonferroni (permeability analysis), to paired t-test (for specimens treated with Icon) and to t-test (DC analysis) (α < 0.05).

RESULTS

Icon showed the lowest LpTreat and LpEro values, while PBC and Gluma did not differ from each other under these conditions. Icon and PBC showed LpEro similar to a dentin with smear layer. Under the Laser Scanning Confocal Microscope, more deposits were noticeable on dentin after treating with PBC. Gluma presented the deepest penetration in dentin. The DC of PBC was the highest.

SIGNIFICANCE

Icon caused the highest reduction on permeability values, followed by PBC and Gluma. PBC generated more deposits covering dentin and seemed to be more efficient after an erosive challenge. The association of a polymeric resin with inorganic ion-releasing fillers seem to be a great strategy to manage dentin hypersensitivity under erosive conditions.

摘要

目的

研究三种不同聚合体在牙本质渗透性受到侵蚀性挑战前后的行为特性,分析它们在这两种条件下的降解情况,并分析其转化率(DC)。

方法

用人牙本质圆盘(1.0±0.2mm)进行测量,有或无玷污层,经 Gluma 脱敏剂、PRG 屏障涂层(PBC)或 Icon 渗透剂处理(LpTreat)后,以及暴露于柠檬酸(LpEro)(6%,pH 值 2.1,1 分钟)后,测量牙本质的渗透性。在激光共聚焦显微镜下分析样本(每组 n=2),并计算产品的 DC。数据采用双向重复测量方差分析和事后 Bonferroni 检验(渗透性分析)、配对 t 检验(Icon 处理的样本)和 t 检验(DC 分析)(α<0.05)。

结果

Icon 显示出最低的 LpTreat 和 LpEro 值,而 PBC 和 Gluma 在这些条件下彼此之间没有差异。Icon 和 PBC 在 LpEro 下与有玷污层的牙本质相似。在激光共聚焦显微镜下,用 PBC 处理后,牙本质上可见更多的沉积物。Gluma 在牙本质中的渗透深度最深。PBC 的 DC 最高。

意义

Icon 导致渗透率值的降低最大,其次是 PBC 和 Gluma。PBC 生成更多覆盖牙本质的沉积物,在受到侵蚀性挑战后似乎更有效。将聚合树脂与无机离子释放填充剂结合使用似乎是在侵蚀性条件下管理牙本质敏感的一种很好的策略。

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