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C 反应蛋白/白蛋白、降钙素原/白蛋白、血小板/淋巴细胞、淋巴细胞/单核细胞比值与住院 COVID-19 患者死亡率的关系。

Association of C-reactive Protein/Albumin, Procalcitonin/Albumin, Platelet/Lymphocyte, and Lymphocyte/Monocyte Ratio with Mortality in Hospitalised COVID-19 Patients.

机构信息

Department of Internal Medicine, Faculty of Medicine, Sakarya University Training and Research Hospital, Sakarya, Turkey.

Department of Internal Medicine, Toyota State Hospital, Sakarya, Turkey.

出版信息

J Coll Physicians Surg Pak. 2022 Sep;32(9):1191-1195. doi: 10.29271/jcpsp.2022.09.1191.

DOI:10.29271/jcpsp.2022.09.1191
PMID:36089719
Abstract

OBJECTIVE

To investigate and compare complete blood count and biochemistry parameters such as c-reactive protein/albumin (CRP/ALB) ratio, procalcitonin/albumin (PRO/ALB) ratio, lymphocyte/monocyte (LYM/MON) ratio, platelet/lymphocyte (PLT/LYM) ratio of the recovered/deceased, and ICU (intensive care unit) /ward patients with COVID-19.

STUDY DESIGN

An observational study.

PLACE AND DURATION OF STUDY

Department of Internal Medicine, Sakarya University Training and Research Hospital, Turkey, from April 2020 to January 2021.

METHODOLOGY

The study was conducted with 590 diagnosed patients with COVID-19. The patients were divided into 2 groups as deceased (n = 294) /survivor (n = 296) and those in need of ICU (n= 418) /ward (n = 172). The information was obtained from the hospital information system and analysed retrospectively. The relationships of crp/alb, pro/alb, lym/mon, and PLT/LYM ratios with patient groups were investigated.

RESULTS

Of the total 590 patients in the study, 358 (60.6%) were males. The total mean age was 65.63 ±14.9 years. The mean age of survivor and deceased groups was 71.32±10.9 and 59.97±16.2 years, respectively (p.

摘要

目的

调查和比较 COVID-19 恢复期/死亡患者、入住 ICU/普通病房患者的全血细胞计数和生化参数,如 C 反应蛋白/白蛋白(CRP/ALB)比值、降钙素原/白蛋白(PRO/ALB)比值、淋巴细胞/单核细胞(LYM/MON)比值、血小板/淋巴细胞(PLT/LYM)比值。

研究设计

观察性研究。

地点和研究时间

土耳其萨卡里亚大学培训与研究医院内科,2020 年 4 月至 2021 年 1 月。

方法

该研究纳入了 590 例确诊为 COVID-19 的患者。患者分为死亡(n=294)/存活(n=296)组和需要入住 ICU(n=418)/普通病房(n=172)组。信息从医院信息系统中获取并进行回顾性分析。研究调查了 CRP/ALB、PRO/ALB、LYM/MON 和 PLT/LYM 比值与患者组之间的关系。

结果

在这项研究的 590 名患者中,有 358 名(60.6%)为男性。总平均年龄为 65.63±14.9 岁。存活组和死亡组的平均年龄分别为 71.32±10.9 岁和 59.97±16.2 岁(p

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