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99mTc-HMPAO as a tumour blood flow agent.

作者信息

Hammersley P A, McCready V R, Babich J W, Coghlan G

出版信息

Eur J Nucl Med. 1987;13(2):90-4. doi: 10.1007/BF00256023.

DOI:10.1007/BF00256023
PMID:3609059
Abstract

The cerebral blood flow agent, 99mTc-HMPAO ('CeretecTM') has been investigated to see if it can be used to estimate tumour blood flow. Its distribution in Balb/c mice bearing either a subcutaneously implanted sarcoma or a plasmacytoma has been shown to be similar to that of 86RbCl. The changes in peripheral blood flow caused by the beta-blocker, propranolol, and by Nembutal anaesthesia, are manifested equally by 99mTc-HMPAO and 86Rb. We conclude, therefore, that HMPAO may be useful in estimating tumour perfusion.

摘要

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本文引用的文献

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Studies on the exchange of fluids between host and tumor. II. The blood flow of hepatomas and other tumors in rats and mice.宿主与肿瘤间体液交换的研究。II. 大鼠和小鼠肝癌及其他肿瘤的血流情况
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