Department of First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Department of Oncology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Front Immunol. 2022 Aug 26;13:1002034. doi: 10.3389/fimmu.2022.1002034. eCollection 2022.
Precision cancer medicine-related rashes are a kind of skin and mucous lesions caused by precision therapy. More and more evidences indicated that such events should not be ignored in the course of anti-tumor therapy. Since cancer treatment entered the "Precision Era", there has been a rapid increase in this field. However, there was few bibliometric studies to provide an overall review of this field. This study aims to evaluate the literature output and trends in researches on precision cancer medicine-related rashes from a global perspective.
Collected publications on precision cancer medicine-related rashes from the Web of Science Core Collection database, which were limited to articles and reviews in English. Microsoft Excel, VOS viewer and CiteSpace V were used for quantitative and visual analysis.
A total of 1,229 papers were identified. From 2008 to 2021, annual publications increased year by year. The United States published the most papers in this field (44.9%) and ranking first in citation frequency (19,854 times) and H-index (69). The University of Texas system ranks first with 98 papers published. Lacouture M.E and Robert C were the principal investigators. Cancers has the largest number of articles published, with 70 articles. In recent years, there have been research hotspots related to immunotherapy, including ipilimumab, immunotherapy, tumor microenvironment, association, checkpoint inhibitor, and cutaneous adverse event.
Precision cancer medicine-related rashes are a hot research topic in oncology. The number of relevant publications will increase dramatically. "Checkpoint inhibitors", "skin adverse events", "associations" and "tumor microenvironment" may become research hotspots in the future.
精准癌症医学相关皮疹是一种由精准治疗引起的皮肤和黏膜损伤。越来越多的证据表明，在抗肿瘤治疗过程中不应忽视此类事件。自癌症治疗进入“精准时代”以来，该领域的研究呈快速增长趋势。然而，很少有文献计量学研究对此领域进行全面综述。本研究旨在从全球角度评估精准癌症医学相关皮疹的文献产出和研究趋势。
从 Web of Science 核心合集数据库中收集关于精准癌症医学相关皮疹的出版物，仅限于英文的文章和综述。使用 Microsoft Excel、VOS viewer 和 CiteSpace V 进行定量和可视化分析。
共确定了 1229 篇论文。从 2008 年到 2021 年，年度出版物逐年增加。美国在该领域发表的论文最多（44.9%），引文频次（19854 次）和 H 指数（69）排名第一。德克萨斯大学系统以发表 98 篇论文排名第一。Lacouture M.E 和 Robert C 是主要研究者。Cancers 杂志发表的文章数量最多，有 70 篇。近年来，与免疫治疗相关的研究热点包括 ipilimumab、免疫治疗、肿瘤微环境、关联、检查点抑制剂和皮肤不良反应。
精准癌症医学相关皮疹是肿瘤学的一个热门研究课题。相关出版物的数量将大幅增加。“检查点抑制剂”、“皮肤不良反应”、“关联”和“肿瘤微环境”可能成为未来的研究热点。
