基于氮杂环系统的直接抗病毒药物的研发

Development of Drugs with Direct Antiviral Action Based on Azaheterocyclic Systems.

作者信息

Charushin V N, Rusinov V L, Varaksin M V, Chupakhin O N, Kovtun O P, Spasov A A

机构信息

Postovskii Institute of Organic Synthesis (IOS), Ural Branch, Russian Academy of Sciences, Yekaterinburg, Russia.

First President of Russia Boris Yeltsin Ural Federal University (UrFU), Yekaterinburg, Russia.

出版信息

Her Russ Acad Sci. 2022;92(4):505-510. doi: 10.1134/S1019331622040104. Epub 2022 Sep 6.

DOI:10.1134/S1019331622040104

PMID:36091844

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9447972/

Abstract

This article discusses the results of studies carried out in recent years by a team of scientists from the Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences, in cooperation with the First President of Russia Boris Yeltsin Ural Federal University, Ural State Medical University, Volgograd State Medical University, and other scientific and production organizations of the country to create triazavirin (riamilovir) and other direct etiotropic antiviral drugs based on azaheterocyclic derivatives.

摘要

本文讨论了俄罗斯科学院乌拉尔分院波斯特ovsky有机合成研究所的一组科学家近年来与俄罗斯第一任总统鲍里斯·叶利钦乌拉尔联邦大学、乌拉尔国立医科大学、伏尔加格勒国立医科大学以及该国其他科研和生产组织合作开展的研究成果，这些研究旨在研发三氮唑韦（瑞米洛韦）及其他基于氮杂环衍生物的直接病因性抗病毒药物。